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2.A.49.5.2
Slow CLC Cl-:H+ antiporter. 3-d structures known at 3.1 Å resolution (3Q17A) (turnover rate: 20/sec; Cl-:H+ stoichiometry = 2:1). The turnover rate of the E. coli EriC is ~2000/sec. (Jayaram et al., 2011).

Accession Number:Q55858
Protein Name:Slr0617 protein
Length:451
Molecular Weight:45789.00
Species:Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) [1148]
Number of TMSs:10
Substrate Cl-, H+

Cross database links:

eggNOG: COG0038
HEGENOM: HBG438996
Entrez Gene ID: 952283   
Pfam: PF00654   
KEGG: syn:slr0617   

Gene Ontology

GO:0016020 C:membrane
GO:0005247 F:voltage-gated chloride channel activity

References (1)

[1] “Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions.”  Kaneko T.et.al.   8905231

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MINGKPQPLL TRVGTWTVGG LLGGLIGSLA AVMLTESIKQ TLSVISGLDP IWLLLIPLFG 
61:	VALAVLVLFG LGKGQPVQTV APREANTPGR WGSLLSWYSF PHDIARADLT GDVVNASGVE 
121:	ERFPWNLAPL RAIAILSTVG FGAPMGTESP AAHIGFATGT WLGSVNSALR PLVRPLAIGG 
181:	GAASVSALMG IPLVGSFFMF ELSGRRQIPL TPERGAAMLA GGLVGWGINV AFNLQLIRLV 
241:	VPKVPPADLW NAMGATLFIG VVTGTITALT GEAIYWARGL RTKPAIRLLA GSLAMLLLAV 
301:	AIAQIATPAA AFGPGGAAIV WAENIETTPY HLLAVAILRA ASTTAAVLAG GCGGVFVPFL 
361:	AIGDLTGRVF ATIFGISGDL AGAAGAAAGI AGGYRLPLTA VAMVLGVGGP ETAQITCLGT 
421:	VVIAAFSGLL AARLANQVSS AIRTIGARNH G