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2.A.49.5.3
Voltage-gated ClC-type chloride channel ClcB or MriT of 418 aas.

Accession Number:Q8FHC1
Protein Name:Voltage-gated ClC-type chloride channel ClcB
Length:418
Molecular Weight:44139.00
Species:Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) [199310]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Cl-

Cross database links:

HEGENOM: HOG000230177
Entrez Gene ID: 1035974   
Pfam: PF00654   
KEGG: ecc:c1983   

Gene Ontology

GO:0034707 C:chloride channel complex
GO:0005886 C:plasma membrane
GO:0005247 F:voltage-gated chloride channel activity
GO:0010447 P:response to acidity

References (1)

[1] “Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.”  Welch R.A.et.al.   12471157

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFRRLLIATI VGILAAFAVA GFRHAMLLLE WLFLNNDSGS LVNAATNLSP WRRLLTPALG 
61:	GLAAGLLLMG WQKFTQQRPH APTDYMEALQ TDGQFDYAAS LVKSLASLLV VTSGSAIGRE 
121:	GAMILLAALA ASCFAQRFTP RQEWKLWIAC GAAAGMAAAY RAPLAGSLFI AEVLFGTMML 
181:	ASLGPVIISA VVALLISNLI NHSDALLYSV QLSVTVQARD YALIISTGVL AGLCGPLLLT 
241:	LMNACHRGFV SLKLAPPWQL ALGGLIVGLL SLFTPAVWGN GYSTVQSFLT APPLLMIIAG 
301:	IFLCKLCAVL ASSGSGAPGG VFTPTLFIGL AIGMLYGRSL GLWLPDGEEI TLLLGLTGMA 
361:	TLLAATTHAP IMSTLMICEM TGEYQLLPGL LIACVIASVI SRTLHRDSIY RQHTAKHS