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2.A.49.6.3
Chloride channel protein CLC-e (AtCLC-e) (CBS domain-containing protein CBSCLC3).  Present in the thylacoid membrane of the chloroplast.  Initially proposed to function in photosynthesis, and later in nitrate assimilation (Herdean et al. 2016).

Accession Number:Q8GX93
Protein Name:Chloride channel protein CLC-e
Length:710
Molecular Weight:75556.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Cl-

Cross database links:

Genevestigator: Q8GX93
eggNOG: COG0038
HEGENOM: HOG000238204
Entrez Gene ID: 829696   
Pfam: PF00571    PF00654   
KEGG: ath:AT4G35440   

Gene Ontology

GO:0034707 C:chloride channel complex
GO:0009535 C:chloroplast thylakoid membrane
GO:0003824 F:catalytic activity
GO:0005247 F:voltage-gated chloride channel activity
GO:0008152 P:metabolic process

References (3)

[1] “Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.”  Mayer K.F.X.et.al.   10617198
[2] “Functional annotation of a full-length Arabidopsis cDNA collection.”  Seki M.et.al.   11910074
[3] “Genome wide expression analysis of CBS domain containing proteins in Arabidopsis thaliana (L.) Heynh and Oryza sativa L. reveals their developmental and stress regulation.”  Kushwaha H.R.et.al.   19400948

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAATLPLCAA LRSPVSSRRF APIHKTDVPF QFNVVLSPFF GSVAIGGRIF PRLPAAKQET 
61:	DQDEVGFDQQ PSQELAIASA CLVGVLTGVS VVLFNNCVHL LRDFSWDGIP DRGASWLREA 
121:	PIGSNWLRVI LVPTIGGLVV SILNQLRESA GKSTGDSHSS LDRVKAVLRP FLKTVAACVT 
181:	LGTGNSLGPE GPSVEIGASI AKGVNSLFNK SPQTGFSLLA AGSAAGISSG FNAAVAGCFF 
241:	AVESVLWPSS STDSSTSLPN TTSMVILSAV TASVVSEIGL GSEPAFKVPD YDFRSPGELP 
301:	LYLLLGALCG LVSLALSRCT SSMTSAVDSL NKDAGIPKAV FPVMGGLSVG IIALVYPEVL 
361:	YWGFQNVDIL LEKRPFVKGL SADLLLQLVA VKIAATAWCR ASGLVGGYYA PSLFIGGAAG 
421:	MAYGKFIGLA LAQNPDFNLS ILEVASPQAY GLVGMAATLA GVCQVPLTAV LLLFELTQDY 
481:	RIVLPLLGAV GMSSWITSGQ SKRQETRETK ETRKRKSQEA VQSLTSSDDE SSTNNLCEVE 
541:	SSLCLDDSLN QSEELPKSIF VSEAMRTRFA TVMMSTSLEE ALTRMLIEKQ SCALIVDPDN 
601:	IFLGILTLSD IQEFSKARKE GNNRPKDIFV NDICSRSGGK CKVPWTVTPD MDLLAAQTIM 
661:	NKHELSHVAV VSGSIDAPRI HPVGVLDREC ITLTRRALAT RMYLLNSLYL