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2.A.49.9.1
Fluoride:proton antiporter of 459 aas and 10 TMSs, CLCF, with high selectivity for fluoride over chloride (Brammer et al. 2014).  These proteins normally exist as dimers, but the monomers are fully active (Last and Miller 2015).

Accession Number:D2QXG0
Protein Name:Chloride channel core
Length:459
Molecular Weight:47986.00
Species:Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) [530564]
Number of TMSs:10
Substrate F-, H+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MQPDSTRHSR MLDIAWRGVR LSLAATVIGV VTGLAVAFFL WSLDQATLLR YEHPWLIYLM 
61:	PLAGVLVALA YQRLCPQAEA GNNLLLEEIH EPAAGVPLWM APLVLLGTLA THVTGGSAGR 
121:	EGTAVQMGGS LAHSVGQWLG IERSEQRTFL MAGMAAGFGA VFGTPVAGAI FAIEVLTHGQ 
181:	LSYRGFLTCL LASIVGDTTT TLCGIGHTEY KIAPWMSAAA GSHLGPLDLV LLLKIVIAAV 
241:	AFGLMARLFA ELTHRTSALL KRYVPWSLAR PAIGAAVVLL LTAIVASRDY LGLGVMPDPH 
301:	DPSLMTIAGC FEEGGAGPMS WAWKTVFTAV TVGSGFKGGE VTPLFFIGAA GGNAMGTLLS 
361:	APLGLLAAVG FVSLFAAATK TPLASTLMGI ELFVHGGDDL VGSGLVIYLA VGCYVASWVS 
421:	GHASIYRSQR IAVPHHPTDE HLAGRSVGNL HEAPPTASH