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2.A.5.1.14
Low affinity zinc-regulated zinc uptake transporter, Zrt2 of 422 aas and 7 TMSs. Active in zinc-replete cells and is time-, temperature- and concentration-dependent.  It prefers zinc over other metals as its substrate (Zhao and Eide 1996).

Accession Number:Q12436
Protein Name:Zinc-regulated transporter 2
Length:422
Molecular Weight:46363.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Zn2+

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVDLIARDDS VDTCQASNGY NGHAGLRILA VFIILISSGL GVYFPILSSR YSFIRLPNWC 
61:	FFIAKFFGSG VIVATAFVHL LQPAAEALGD ECLGGTFAEY PWAFGICLMS LFLLFFTEII 
121:	THYFVAKTLG HDHGDHGEVT SIDVDAPSSG FVIRNMDSDP VSFNNEAAYS IHNDKTPYTT 
181:	RNEEIVATPI KEKEPGSNVT NYDLEPGKTE SLANELVPTS SHATNLASVP GKDHYSHEND 
241:	HQDVSQLATR IEEEDKEQYL NQILAVFILE FGIIFHSVFV GLSLSVAGEE FETLFIVLTF 
301:	HQMFEGLGLG TRVAETNWPE SKKYMPWLMG LAFTLTSPIA VAVGIGVRHS WIPGSRRALI 
361:	ANGVFDSISS GILIYTGLVE LMAHEFLYSN QFKGPDGLKK MLSAYLIMCC GAALMALLGK 
421:	WA