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2.A.5.1.8
Zinc-regulated transporter 1 (High-affinity zinc transport (uptake) protein Zrt1) (Boch et al. 2008).

Accession Number:O94639
Protein Name:Zinc-regulated transporter 1
Length:408
Molecular Weight:45272.00
Species:Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [284812]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate Zn2+

Cross database links:

eggNOG: NOG306665
HEGENOM: HOG000157076
Entrez Gene ID: 2539655   
Pfam: PF02535   
KEGG: spo:SPBC16D10.0   

Gene Ontology

GO:0005783 C:endoplasmic reticulum
GO:0005789 C:endoplasmic reticulum membrane
GO:0016021 C:integral to membrane
GO:0005385 F:zinc ion transmembrane transporter activity
GO:0071276 P:cellular response to cadmium ion
GO:0034224 P:cellular response to zinc ion starvation
GO:0006830 P:high-affinity zinc ion transport
GO:0033217 P:regulation of transcription from RNA polymerase II promoter in response to iron ion starvation
GO:0055069 P:zinc ion homeostasis

References (4)

[1] “The genome sequence of Schizosaccharomyces pombe.”  Wood V.et.al.   11859360
[2] “ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.”  Matsuyama A.et.al.   16823372
[3] “Response of Schizosaccharomyces pombe to zinc deficiency.”  Dainty S.J.et.al.   18203864
[4] “Phosphoproteome analysis of fission yeast.”  Wilson-Grady J.T.et.al.   18257517

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSLNNLSNSY NQYLAQESHQ ILRHLFLNKQ YSPLVKRDDD SSATVTCGGD ANEFNEYGHL 
61:	GYRIGAIFVI LATSLIGMNL PLVLSKITKN RPNVYIEYLY LFARYFGSGV ILATAFIHLL 
121:	APACNKLYDP CLDDLFGGYD WAPGICLISC WFILLLEVLL NRYVEWRFGM EIGDHHGPTL 
181:	GAKQHSHSHE DGAHGVHEHP VYDIEECADG VEHECVKDDL EEVKLEPYTN TDSTDLTTKE 
241:	EARSFLLKQQ LTAFIILESS IILHSVIIGL TTAVSGEEFK TLFPVIIFHQ AFEGCGLGSR 
301:	LAGMAWGPKT AWVPWVLGVI YSLVTPIGMA AGLGVREHWD PLAHGSYAAQ GVLDAISSGI 
361:	LVYAGLVELL AHDFLFSPER ERNWYKLIYL LACSMAGTGV MALLGKWA