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2.A.5.3.3
Zn2+ uptake transporter, Zip3 (poorly expressed; involved in Zn2+ homeostasis) (Dufner-Beattie et al., 2003).

Accession Number:Q9BRY0
Protein Name:Solute carrier family 39 member 3 aka Zip3
Length:314
Molecular Weight:33601.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Zn2+

Cross database links:

Genevestigator: Q9BRY0 Q9BRY0 Q9BRY0
eggNOG: prNOG10141 KOG1558 KOG1558
RefSeq: NP_653165.2    NP_998733.1   
Entrez Gene ID: 29985   
Pfam: PF02535   
KEGG: hsa:29985    hsa:29985    hsa:29985   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0055085 P:transmembrane transport
GO:0006829 P:zinc ion transport
GO:0005886 C:plasma membrane
GO:0046873 F:metal ion transmembrane transporter activity

References (18)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[4] “A quantitative atlas of mitotic phosphorylation.”  Dephoure N.et.al.   18669648
[5] “Large-scale proteomics analysis of the human kinome.”  Oppermann F.S.et.al.   19369195
[6] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332
[7] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[8] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[9] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[10] “A quantitative atlas of mitotic phosphorylation.”  Dephoure N.et.al.   18669648
[11] “Large-scale proteomics analysis of the human kinome.”  Oppermann F.S.et.al.   19369195
[12] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332
[13] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[14] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[15] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[16] “A quantitative atlas of mitotic phosphorylation.”  Dephoure N.et.al.   18669648
[17] “Large-scale proteomics analysis of the human kinome.”  Oppermann F.S.et.al.   19369195
[18] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVKLLVAKIL CMVGVFFFML LGSLLPVKII ETDFEKAHRS KKILSLCNTF GGGVFLATCF 
61:	NALLPAVREK LQKVLSLGHI STDYPLAETI LLLGFFMTVF LEQLILTFRK EKPSFIDLET 
121:	FNAGSDVGSD SEYESPFMGG ARGHALYVEP HGHGPSLSVQ GLSRASPVRL LSLAFALSAH 
181:	SVFEGLALGL QEEGEKVVSL FVGVAVHETL VAVALGISMA RSAMPLRDAA KLAVTVSAMI 
241:	PLGIGLGLGI ESAQGVPGSV ASVLLQGLAG GTFLFITFLE ILAKELEEKS DRLLKVLFLV 
301:	LGYTVLAGMV FLKW