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2.A.5.3.5
Zinc transporter ZIP1 (DrZIP1) (Solute carrier family 39 member 1) (Zrt- and Irt-like protein 1) (ZIP-1)

Accession Number:P59889
Protein Name:Zinc transporter ZIP1
Length:302
Molecular Weight:32822.00
Species:Danio rerio (Zebrafish) [7955]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Zn2+

Cross database links:

eggNOG: NOG84653
HEGENOM: HOG000236331
Entrez Gene ID: 321324   
Pfam: PF02535   
KEGG: dre:321324   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0046873 F:metal ion transmembrane transporter activity
GO:0008270 F:zinc ion binding
GO:0071577 P:zinc ion transmembrane transport

References (1)

[1] “Molecular cloning and functional characterization of a high-affinity zinc importer (DrZIP1) from zebrafish (Danio rerio).”  Qiu A.et.al.   15683366

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDYLLQVKVG ALVGLLLLTL FFGFIPARMK WFHVTGGTEL HKAVLSFVSC FAGGVFLSAC 
61:	LLDIIPDYLS DIHGELQKRD LDDGFPLPEF IMACGFFTVL ILEKMVLSCT EGHRNEETAP 
121:	LLAPAAPNGH AHGHPSVNDL EGSGHHVHVD FHAHSSFRSF MLFLSLSLHS VFEGLAIGLQ 
181:	TTNAKVLEIC IAILVHKSII VFSLSVKLVQ SAVKPLWVVL YVTVFAIMSP LGIGIGIVVI 
241:	ETERQAGGLI QAVLEGLAAG TFIYITFLEI LPHELNSSER PLLKVLFLLC GFSIMAALCF 
301:	LG