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2.A.5.4.2
Zinc transporter, LIV1 (essential for the nuclear localization of the zinc-finger protein Snail, a master regulator of the epithelial-mesenchymal transition in zebrafish gastrulation) (Yamashita et al., 2004)

Accession Number:Q6L8F3
Protein Name:Zinc transporter LIV1
Length:742
Molecular Weight:83030.00
Species:Brachydanio rerio (Zebrafish) (Danio rerio) [7955]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Apical cell membrane1 / Multi-pass membrane protein2
Substrate Zn2+

Cross database links:

eggNOG: fiNOG05474
RefSeq: NP_001001591.1   
Entrez Gene ID: 324303   
Pfam: PF02535   
KEGG: dre:324303   

Gene Ontology

GO:0016020 C:membrane
GO:0046873 F:metal ion transmembrane transporter activity
GO:0030001 P:metal ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer.”  Yamashita S.et.al.   15129296

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMTFLCTRSG RRASGVECRI AAERAYFRVR GLPVANMIGW WPRLCPVMSL ALLWACSVGA 
61:	GSDCKSVAIE TDSRIAEQTQ QRHLQALFDK YGQNGSISLE GLFNLLKGVG LDRIRKVMVH 
121:	HPGNAHNHTH THDHTHTHVD KLTAHTHPVT TKKGDMDHSV EKSDPVPKAQ PDPASGKKSQ 
181:	SDAHHNLYMK MNQESTTALT TPSYVTRSRR TNRSADYDFT QDHASFSPSQ PNVTHSNHTH 
241:	HDEDTPTHQH DDHDEHEHAR ASLGCQNAST ILQTHGMRKE ASLSVKDFSF LCPALLMQID 
301:	SKSCIVHEDE DEHSDHSHHH KHHHHHHDHQ HLQHPHNHTN GRGQRNTPVY IAWLGGFLSI 
361:	TLISLLALVG VVLIPLMNRV CFNFLLSFLV ALAVGTLSGD ALLHLIPHSQ GHHHHGHSEE 
421:	HAEEEDSLRP VWTGLTALSG VYIMFLIEHF LTLGKMYKDK NQKVQKRVDL TTEVLESEKL 
481:	PSLEENDVKI EAAETNGGRA LAEEEEVMLG AELYNDIDCE NKCHSHFHDT VGQSDEQHHH 
541:	HHDYHHILHH HHSQNHHPHT HTHRHTHSYS QQHFEQAGVA TLAWMVIMGD GLHNFSDGLA 
601:	IGAAFTEGLS SGLSTSVAVF CHELPHELGD FAVLLKAGMS VRQAMLYNLL SALMGYLGMI 
661:	IGILIGHYAE NVATWIFALT AGLFMYVALV DMVPEMLHND ASEAGFSHYG FFLLQNAGIL 
721:	LGFGIMLIIA VFEDRIQLDL GY