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2.A.5.4.7
The indole acetic acid-alanine resistance protein 1, Iar1 (Lasswell et al., 2000)

Accession Number:Q9M647
Protein Name:Iar1 - IAA-alanine resistance protein 1
Length:469
Molecular Weight:50583.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Indole-3-acetic acid-alanine

Cross database links:

Genevestigator: Q9M647
eggNOG: KOG2693
HEGENOM: HBG715717
RefSeq: NP_564921.1   
Entrez Gene ID: 843138   
Pfam: PF02535   
KEGG: ath:AT1G68100   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0046873 F:metal ion transmembrane transporter activity
GO:0030001 P:metal ion transport
GO:0055085 P:transmembrane transport

References (3)

[1] “Cloning and characterization of IAR1, a gene required for auxin conjugate sensitivity in Arabidopsis.”  Lasswell J.E.et.al.   11148286
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSFSLRKLLV PILVLVLFLD LCVESGFSQS TPARDDHVHH HGGGCSHSHD HDHDHDHDHH 
61:	VKKTTAKVEM KLPEELAEEE DMRLCGFGPC LHDHDHESSS TLTGFALWLN ALGCSLLVSL 
121:	ASLICLVLLP IMFVQGKPSK WFVDSLALFG AGAMLGDAFL HQLPHAFGGG HSHSNDHHEN 
181:	HDHHDHSHSD SPSHSHSIQD LSVGLSVLAG IVVFLLVEKL VRYVEENSSG SNTWGHHHHH 
241:	HHAGSKKLKD EGDHNNLDQQ SSSDAIVNSS EKVSGGSTDK SLRKRKTSAS DATDKSDSGT 
301:	EITSDGKSDK PEQVETRSSS LVFGYLNLFS DGVHNFTDGM ALGSAFLIYG SVGGWSRTMF 
361:	LLAHELPQEI GDFGILVRSG FTVTKALFFN FLSALVALAG TALVLVWGNE PGQSSLIEGF 
421:	TAGGFIYIAV AGVLAEMNNS GKSTLKNSAC HLISLILGMS VALCISLIE