TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.5.5.2
Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11)

Accession Number:Q8N1S5
Protein Name:Zinc transporter ZIP11
Length:342
Molecular Weight:35396.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Zn2+

Cross database links:

Genevestigator: Q8N1S5
eggNOG: COG0428
HEGENOM: HOG000232703
Entrez Gene ID: 201266   
Pfam: PF02535   
KEGG: hsa:201266   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0046873 F:metal ion transmembrane transporter activity
GO:0006829 P:zinc ion transport

References (4)

[1] “Comparative genomics of the SOX9 region in human and Fugu rubripes: conservation of short regulatory sequence elements within large intergenic regions.”  Bagheri-Fam S.et.al.   11707075
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.”  Zody M.C.et.al.   16625196
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MLQGHSSVFQ ALLGTFFTWG MTAAGAALVF VFSSGQRRIL DGSLGFAAGV MLAASYWSLL 
61:	APAVEMATSS GGFGAFAFFP VAVGFTLGAA FVYLADLLMP HLGAAEDPQT TLALNFGSTL 
121:	MKKKSDPEGP ALLFPESELS IRIGRAGLLS DKSENGEAYQ RKKAAATGLP EGPAVPVPSR 
181:	GNLAQPGGSS WRRIALLILA ITIHNVPEGL AVGVGFGAIE KTASATFESA RNLAIGIGIQ 
241:	NFPEGLAVSL PLRGAGFSTW RAFWYGQLSG MVEPLAGVFG AFAVVLAEPI LPYALAFAAG 
301:	AMVYVVMDDI IPEAQISGNG KLASWASILG FVVMMSLDVG LG