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2.A.5.6.1
Zip family member, ZIP9 (SLC39A9) (307aas; 8 TMSs).  The orthologue, Zip9, in the atlantic croaker (Micropogonias undulatus) is an androgen receptor that mediates testosterone-induced apoptosis of female ovarian follicle cells (Berg et al. 2014).

Accession Number:Q9NUM3
Protein Name:Zinc transporter ZIP9
Length:307
Molecular Weight:32251.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Zn2+

Cross database links:

Genevestigator: Q9NUM3 Q9NUM3
eggNOG: prNOG13850 NOG82920
HEGENOM: HBG396629 HOG000164405
Entrez Gene ID: 55334   
Pfam: PF02535   
KEGG: hsa:55334    hsa:55334   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0046873 F:metal ion transmembrane transporter activity
GO:0055085 P:transmembrane transport
GO:0006829 P:zinc ion transport

References (6)

[1] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”  Clark H.F.et.al.   12975309
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”  Clark H.F.et.al.   12975309
[5] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDDFISISLL SLAMLVGCYV AGIIPLAVNF SEERLKLVTV LGAGLLCGTA LAVIVPEGVH 
61:	ALYEDILEGK HHQASETHNV IASDKAAEKS VVHEHEHSHD HTQLHAYIGV SLVLGFVFML 
121:	LVDQIGNSHV HSTDDPEAAR SSNSKITTTL GLVVHAAADG VALGAAASTS QTSVQLIVFV 
181:	AIMLHKAPAA FGLVSFLMHA GLERNRIRKH LLVFALAAPV MSMVTYLGLS KSSKEALSEV 
241:	NATGVAMLFS AGTFLYVATV HVLPEVGGIG HSHKPDATGG RGLSRLEVAA LVLGCLIPLI 
301:	LSVGHQH