TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*2.A.50.1.1









Putative glycerol:H+ symporter of 546 aas and 12 TMSs, GUP1.  In yeast, Gup1 is associated with a high number and diversity of biological functions, namely polarity establishment, secretory/endocytic pathway functionality, vacuole morphology, wall and membrane composition, structure and maintenance, cell death, morphogenesis and differentiation (Lucas et al. 2016). The protein HHAT (Hedgehog O-acyltransferase) modifies Hh morphogens prior to their secretion, while HHATL (Hh O-acyltransferase-like) negatively regulates the pathway. HHAT and HHATL are homologous to Saccharomyces cerevisiae Gup2 and Gup1, respectively (Lucas et al. 2016).

Eukaryota
Fungi
GUP1 of Saccharomyces cerevisiae
*2.A.50.1.2









Protein-cysteine N-palmitoyltransferase HHAT-like protein (Glycerol uptake/transporter homologue) (Hedgehog acyltransferase-like protein)

Eukaryota
Metazoa
HHATL protein of Mus musculus
*2.A.50.1.3









Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Skinny hedgehog protein)
Eukaryota
Metazoa
Hhat of Mus musculus
*2.A.50.2.1









The putative alanyl teichoic acid synthesis protein, DltB (may transport activated alanine across the membrane (Perego et al., 1995)
Bacteria
Firmicutes
DltB of Bacillus subtilis (P39580)