TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.53.1.10
solute carrier family 26, member 11

Accession Number:Q86WA9
Protein Name:Sodium-independent sulfate anion transporter
Length:606
Molecular Weight:65299.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: Q86WA9 Q86WA9
eggNOG: COG0659 COG0659
Entrez Gene ID: 284129   
Pfam: PF01740    PF00916   
KEGG: hsa:284129    hsa:284129   

Gene Ontology

GO:0005783 C:endoplasmic reticulum
GO:0005794 C:Golgi apparatus
GO:0016021 C:integral to membrane
GO:0005765 C:lysosomal membrane
GO:0005886 C:plasma membrane
GO:0015301 F:anion:anion antiporter activity
GO:0008271 F:secondary active sulfate transmembrane transporter activity
GO:0008509 F:anion transmembrane transporter activity
GO:0008272 P:sulfate transport

References (14)

[1] “Molecular and functional characterization of SLC26A11, a sodium-independent sulfate transporter from high endothelial venules.”  Vincourt J.-B.et.al.   12626430
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”  Otsuki T.et.al.   16303743
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[5] “Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger.”  Lohi H.et.al.   11087667
[6] “Integral and associated lysosomal membrane proteins.”  Schroeder B.et.al.   17897319
[7] “The proteome of lysosomes.”  Schroeder B.A.et.al.   20957757
[8] “Molecular and functional characterization of SLC26A11, a sodium-independent sulfate transporter from high endothelial venules.”  Vincourt J.-B.et.al.   12626430
[9] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[10] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”  Otsuki T.et.al.   16303743
[11] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[12] “Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger.”  Lohi H.et.al.   11087667
[13] “Integral and associated lysosomal membrane proteins.”  Schroeder B.et.al.   17897319
[14] “The proteome of lysosomes.”  Schroeder B.A.et.al.   20957757

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MPSSVTALGQ ARSSGPGMAP SACCCSPAAL QRRLPILAWL PSYSLQWLKM DFVAGLSVGL 
61:	TAIPQALAYA EVAGLPPQYG LYSAFMGCFV YFFLGTSRDV TLGPTAIMSL LVSFYTFHEP 
121:	AYAVLLAFLS GCIQLAMGVL RLGFLLDFIS YPVIKGFTSA AAVTIGFGQI KNLLGLQNIP 
181:	RPFFLQVYHT FLRIAETRVG DAVLGLVCML LLLVLKLMRD HVPPVHPEMP PGVRLSRGLV 
241:	WAATTARNAL VVSFAALVAY SFEVTGYQPF ILTGETAEGL PPVRIPPFSV TTANGTISFT 
301:	EMVQDMGAGL AVVPLMGLLE SIAVAKAFAS QNNYRIDANQ ELLAIGLTNM LGSLVSSYPV 
361:	TGSFGRTAVN AQSGVCTPAG GLVTGVLVLL SLDYLTSLFY YIPKSALAAV IIMAVAPLFD 
421:	TKIFRTLWRV KRLDLLPLCV TFLLCFWEVQ YGILAGALVS LLMLLHSAAR PETKVSEGPV 
481:	LVLQPASGLS FPAMEALREE ILSRALEVSP PRCLVLECTH VCSIDYTVVL GLGELLQDFQ 
541:	KQGVALAFVG LQVPVLRVLL SADLKGFQYF STLEEAEKHL RQEPGTQPYN IREDSILDQK 
601:	VALLKA