TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.53.1.6
The sulfate transporter, Sultr1.2 with C-terminal STAS domain that is required both for activity and biogenesis/stability (Shibagaki and Grossman, 2006). It physically interacts with 0-acetylserine (thiol)lyase (cysteine synthetase) via its STAS domain. This interaction stimulates the activity of 0-acetylserine (thiol)lyase while inhibiting the SULTR1;2 transport activity. SULTR1.1 (TC# 2.A.53.1.7) interacts with 0-acetylserine (thiol)lyase but this interaction does not stimulate its activity (Shibagaki and Grossman, 2010).

Accession Number:Q9MAX3
Protein Name:Sultr1;2
Length:653
Molecular Weight:71707.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Sulfate

Cross database links:

Genevestigator: Q9MAX3
HEGENOM: HBG554309
RefSeq: NP_565166.1    NP_849899.1   
Entrez Gene ID: 844135   
Pfam: PF01740    PF00916   
KEGG: ath:AT1G78000   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008271 F:secondary active sulfate transmembrane tran...
GO:0015293 F:symporter activity
GO:0009970 P:cellular response to sulfate starvation
GO:0008272 P:sulfate transport
GO:0055085 P:transmembrane transport

References (3)

[1] “Two distinct high-affinity sulfate transporters with different inducibilities mediate uptake of sulfate in Arabidopsis roots.”  Yoshimoto N.et.al.   11846879
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Selenate-resistant mutants of Arabidopsis thaliana identify Sultr1;2, a sulfate transporter required for efficient transport of sulfate into roots.”  Shibagaki N.et.al.   11846880

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSSRAHPVDG SPATDGGHVP MKPSPTRHKV GIPPKQNMFK DFMYTFKETF FHDDPLRDFK 
61:	DQPKSKQFML GLQSVFPVFD WGRNYTFKKF RGDLISGLTI ASLCIPQDIG YAKLANLDPK 
121:	YGLYSSFVPP LVYACMGSSR DIAIGPVAVV SLLLGTLLRA EIDPNTSPDE YLRLAFTATF 
181:	FAGITEAALG FFRLGFLIDF LSHAAVVGFM GGAAITIALQ QLKGFLGIKK FTKKTDIISV 
241:	LESVFKAAHH GWNWQTILIG ASFLTFLLTS KIIGKKSKKL FWVPAIAPLI SVIVSTFFVY 
301:	ITRADKQGVQ IVKHLDQGIN PSSFHLIYFT GDNLAKGIRI GVVAGMVALT EAVAIGRTFA 
361:	AMKDYQIDGN KEMVALGMMN VVGSMSSCYV ATGSFSRSAV NFMAGCQTAV SNIIMSIVVL 
421:	LTLLFLTPLF KYTPNAILAA IIINAVIPLI DIQAAILIFK VDKLDFIACI GAFFGVIFVS 
481:	VEIGLLIAVS ISFAKILLQV TRPRTAVLGN IPRTSVYRNI QQYPEATMVP GVLTIRVDSA 
541:	IYFSNSNYVR ERIQRWLHEE EEKVKAASLP RIQFLIIEMS PVTDIDTSGI HALEDLYKSL 
601:	QKRDIQLILA NPGPLVIGKL HLSHFADMLG QDNIYLTVAD AVEACCPKLS NEV