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2.A.53.2.2
Canicular sulfate:HCO3- antiporter (Slc26a1)

Accession Number:P45380
Protein Name:SAT1 aka SLC26A1
Length:703
Molecular Weight:75447.00
Species:Rattus norvegicus (Rat) [10116]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Sulfate, bicarbonate

Cross database links:

Genevestigator: P45380
eggNOG: roNOG14281
Pfam: PF01740    PF00916   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015297 F:antiporter activity
GO:0008271 F:secondary active sulfate transmembrane tran...
GO:0008272 P:sulfate transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Functional expression cloning of the canalicular sulfate transport system of rat hepatocytes.”  Bissig M.et.al.   8300633

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MDASPEPPQK GGTLVLVRRQ PPVSQGLLET LKARLKKSCT CSMPCAQALV QGLFPVIRWL 
61:	PQYRLKEYLA GDVMSGLVIG IILVPQAIAY SLLAGLQPIY SLYTSFFANL IYFLMGTSRH 
121:	VNVGIFSLLC LMVGQVVDRE LQLAGFDPSQ DSLGPGNNDS TLNNTATLTV GLQDCGRDCH 
181:	AIRIATALTL MAGLYQVLMG ILRLGFVSTY LSQPLLDGFA MGASVTILTS QAKHLLGVRI 
241:	PRHQGLGMVI HTWLSLLQNV GQANLCDVVT SAVCLAVLLT AKELSDRYRH YLKVPVPTEL 
301:	LVIVVATIAS HFGQLHTRFG SSVAGNIPTG FVAPQIPDPK IMWSVALDAM SLALVGSAFS 
361:	ISLAEMFARS HGYSVSANQE LLAVGCCNVL PAFFHCFATS AALSKTLVKI ATGCQTQLSS 
421:	VVSAAVVLLV LLVLAPLFHD LQRCVLACII VVSLRGALRK VKDLPQLWRL SPADALVWVA 
481:	TAATCVLVSI EAGLLAGVFF SLLSLAGRTQ RPRAALLARI GDSTFYEDAA EFEGLLPPPE 
541:	VRVFRFTGPL YYANKDFFLR SLYSLTGLDA GYSATRKDRG TEVGVSNRSL VDRKDLGSVS 
601:	SGDGLVVPLA FGFHTVVIDC APLLFLDVAG MATLKDLRKN YRALDITLLL ACCSPSVRDT 
661:	LRKGGFLGED QGTAEELLFP SVHSAVETAC ARREELMAAD SAL