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2.A.53.2.9
The electrogenic divalent anion: chloride exchanger (1:1 stoichiometry) (transports sulfate, chloride, and oxalate) (Schaechinger and Oliver, 2007)

Accession Number:A0FKN5
Protein Name:Prestin
Length:742
Molecular Weight:81113.00
Species:Gallus gallus (Chicken) [9031]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Sulfate, Cl-, Oxalate

Cross database links:

eggNOG: veNOG06447
HEGENOM: HBG446299
RefSeq: NP_001072945.1   
Entrez Gene ID: 417715   
Pfam: PF01740    PF00916   
KEGG: gga:417715   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008271 F:secondary active sulfate transmembrane tran...
GO:0008272 P:sulfate transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Nonmammalian orthologs of prestin (SLC26A5) are electrogenic divalent/chloride anion exchangers.”  Schaechinger T.J.et.al.   17442754
Structure:
5EZB     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MEDAQESGEC LVQNQKYCVE RPIYNQEILQ GQLHKRERTP QSLRQKIEHS CRCSSKKAKS 
61:	HLYSFLPILK WLPRYPVKEY LLGDIISGIS TGVMQLPQGL AYALLAAVPP VFGLYSSFYP 
121:	VFLYTFFGTS KHISIGTFAV ISMMVGGVAV RQVPDEVISV GYNSTNATDA SDYYSLRDDK 
181:	RVQVAVTLAF LSGIIQLCLG FLRFGFVAIY LTEPLVRGFT TAAAVHVFTS QLKYLLGVKT 
241:	SRYSGPLSVV YSLVAVFSKI TTTNIAALIV GLTCIALLLI GKEINLRFKK KLPVPIPMEI 
301:	IVVIIGTGVS AGMNLTESYG VDVVGKIPQG LSAPAVPEIQ LIPAIFIDAV AIAIVGFSMA 
361:	VSMAKIFALK HGYTIDGNQE LIALGICNSV GSFFQSFPIT CSMSRSLVQE STGGKTQIAG 
421:	ALSSIMVLLV IVAIGYLFEP LPQTVLAAIV MVNLKGMFKQ FADVAHFWRT SKIELAIWVV 
481:	AFVASLFLGL DYGLLTAVAF AMITVIYRTQ RPQYRILGQI PDTDIYCDVE EYEEVKEYPG 
541:	IKIFQANTSL YFANSESYTS ALKKKTGVDP CAILAARRKA QKKHAREIKK ANKVKKKAVL 
601:	KLVNSSTNDV EASVKHEIAN DGLPANGKFA FVDAGVQDGS PDELEHFVEP KTNVHSLILD 
661:	FAPVNFVDSV GAKTLKSVIK EYNEVGVCVC IASCSGPVMN ELTRLNFFDN TVTRELLFHS 
721:	IHDAVLACQG KDRSASQTAL DH