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2.A.53.3.2
Bicarbonate:Na+ symporter, BicA (Price et al., 2004).  The protein probably has 14 TMSs in a 7 + 7 arrangement (Price and Howitt 2014).

Accession Number:Q7U617
Protein Name:BicA
Length:556
Molecular Weight:57666.00
Species:Synechococcus sp. (strain WH8102) [84588]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate bicarbonate, Na+

Cross database links:

eggNOG: COG0659
HEGENOM: HBG564176
RefSeq: NP_897617.1   
Entrez Gene ID: 1730941   
Pfam: PF01740    PF00916   
BioCyc: SSP84588:SYNW1524OR3155-MONOMER   
KEGG: syw:SYNW1524   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “The genome of a motile marine Synechococcus.”  Palenik B.et.al.   12917641

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MTLGRIVLNR INATNLKGDV FGGLTAAVIA LPMALAFGIA SGAGAAAGLW GAVIIGLVAS 
61:	LFGGTPTLIS EPTGPMTVVF TSVIISFTAT ADSPEQALAM AFSVGVLAGI FQILFGLFRL 
121:	GRYVTMMPYT VISGFMSGIG IILVLLQLGP FLGQATPKGG VMGTLLEMPA LVQGTQPMEL 
181:	LLALITLAIL WFTPSAVKKV CPPQLLALVV GTVLALSLFS GAGLRTIPEF SAALPSFQLP 
241:	TFSSGQLRLM VIDAAVLGML GCIDALLTSV VADSLTRTEH NSNKELIGQG LANVVSGLFG 
301:	AMPGAGATMG TVVNIQSGGR TALSGIVRAM VLMLVVLLAA PLASRIPLAV LAGIAVKVGI 
361:	DIMDWDFLQR AHHLSVKAAV ITYGVIALTV LVDLIAAVGI GVFVANVLTI DRMSTLQSKK 
421:	VKTISTTDDD VELSDEEQQL LDRASGMVLL FQLAGPMIFG VAKAISREHN AIGNCQAVVF 
481:	DLSEVSHLGV TAAIALENAV KEAMEVGRDV FMVGVSGSTE NRLRKLKLLE RLPEGHLTSD 
541:	RLSALRLAVA GLPAHG