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2.A.53.3.3
12 TMS Na+:bicarbonate symporter, BicA (Price et al., 2004; Shelden et al., 2010) (low affinity but high efficiency).

Accession Number:Q14SY0
Protein Name:BicA
Length:566
Molecular Weight:59605.00
Species:Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) [32049]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Na+, bicarbonate

Cross database links:

HEGENOM: HBG564176 HBG564176
RefSeq: YP_001735604.1   
Entrez Gene ID: 6057852   
Pfam: PF01740    PF00916   
KEGG: syp:SYNPCC7002_    syp:SYNPCC7002_   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (2)

[1] “Identification of a SulP-type bicarbonate transporter in marine cyanobacteria.”  Price G.D.et.al.   15596724
[2] “Identification of a SulP-type bicarbonate transporter in marine cyanobacteria.”  Price G.D.et.al.   15596724

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MQITNKIHFR NIRGDIFGGL TAAVIALPMA LAFGVASGAG AEAGLWGAVL VGFFAALFGG 
61:	TPTLISEPTG PMTVVMTAVI AHFTASAATP EEGLAIAFTV VMMAGVFQII FGSLKLGKYV 
121:	TMMPYTVISG FMSGIGIILV ILQLAPFLGQ ASPGGGVIGT LQNLPTLLSN IQPGETALAL 
181:	GTVAIIWFMP EKFKKVIPPQ LVALVLGTVI AFFVFPPEVS DLRRIGEIRA GFPELVRPSF 
241:	SPVEFQRMIL DAAVLGMLGC IDALLTSVVA DSLTRTEHNS NKELIGQGLG NLFSGLFGGI 
301:	AGAGATMGTV VNIQSGGRTA LSGLVRAFVL LVVILGAASL TATIPLAVLA GIAFKVGVDI 
361:	IDWSFLKRAH EISPKGALIM YGVILLTVLV DLIVAVGVGV FVANVLTIER MSNLQSEKVQ 
421:	TVSDADDNIR LTTTEKRWLD EGQGRVLLFQ LSGPMIFGVA KAIAREHNAM GDCDALVFDI 
481:	GEVPHMGVTA SLALENAIEE ALDKERQVYI VGAAGQTRRR LEKLKLFKRV PPDKCLMSRE 
541:	EALKNAVLGI YPHLADGVTA PSSEMG