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2.A.53.4.2
Sulfate transporter, Rv1739c (Zolotarev et al. 2008).  Its STAS domain binds guanine nucleotides as shown by x-ray chrystalography (PDB# 2KLN; Sharma et al. 2011; Sharma et al. 2012).  Sulfate uptake by Rv1739c requires CysA and its associated sulfate permease activity, and suggest that Rv1739c may be a CysTWA-dependent sulfate transport protein (Sharma et al. 2012).  Sulfate uptake by Rv1739c requires CysA and its associated sulfate permease activity, and suggest that Rv1739c may be a CysTWA-dependent sulfate transport protein (Zolotarev et al. 2008).

Accession Number:P71997
Protein Name:Probable sulfate transporter Rv1739c/MT1781
Length:560
Molecular Weight:59367.00
Species:Mycobacterium tuberculosis [1773]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Sulfate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIPTMTSAGW APGVVQFREY QRRWLRGDVL AGLTVAAYLI PQAMAYATVA GLPPAAGLWA 
61:	SIAPLAIYAL LGSSRQLSIG PESATALMTA AVLAPMAAGD LRRYAVLAAT LGLLVGLICL 
121:	LAGTARLGFL ASLRSRPVLV GYMAGIALVM ISSQLGTITG TSVEGNEFFS EVHSFATSVT 
181:	RVHWPTFVLA MSVLALLTML TRWAPRAPGP IIAVLAATML VAVMSLDAKG IAIVGRIPSG 
241:	LPTPGVPPVS VEDLRALIIP AAGIAIVTFT DGVLTARAFA ARRGQEVNAN AELRAVGACN 
301:	IAAGLTHGFP VSSSSSRTAL ADVVGGRTQL YSLIALGLVV IVMVFASGLL AMFPIAALGA 
361:	LVVYAALRLI DLSEFRRLAR FRRSELMLAL ATTAAVLGLG VFYGVLAAVA LSILELLRRV 
421:	AHPHDSVLGF VPGIAGMHDI DDYPQAKRVP GLVVYRYDAP LCFANAEDFR RRALTVVDQD 
481:	PGQVEWFVLN AESNVEVDLT ALDALDQLRT ELLRRGIVFA MARVKQDLRE SLRAASLLDK 
541:	IGEDHIFMTL PTAVQAFRRR