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2.A.55.2.10
NRAMP2 (SLC11a2) of 552 aas and 10 TMSs.  Inovoled in iron hoemeostasis and infectivity together with NRAMP1 (TC#2.A.55.2.9).  Present in the contractile vacuole which regulates osmolarity and possible stores iron (Peracino et al. 2013).

Accession Number:Q553K4
Protein Name:Natural resistance-associated macrophage protein 2 homolog
Length:629
Molecular Weight:70404.00
Species:Dictyostelium discoideum (Slime mold) [44689]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Fe2+

Cross database links:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNNNNNNKKL NKENLNEIEN WNEIELTDYK KQGLDEGTSS NIYLFESNGN VVNGSIEDSP 
61:	KQQQQQQQQQ QQQQQQQQQQ QQQQQNIISS DEEIEDKPFQ DRDSNIGDGS DIDSSGDSID 
121:	IENTDYSILV PFEDEENNNG SKSKFSIKKL KSFLGPALFI SVGYMDPGNW ATDLEGGSRF 
181:	GYQLMWVLLF SNIMALFLQT LVIKLALVTK NDLAQQCRKE YSKTVNIFLW LILELAIIST 
241:	DLAEVIGTAI GLNILFGLPL IAGVAITSLD TLLFLAIQRW GIRKLELLIL LLLSMITMCF 
301:	VIELFLSKPI ASEVFSGFVP RLNSDSVMVA TGIVGATTMP HNLFLHGSVV KSRKIPNDRR 
361:	KSVIKQAYRY NVIDTVLALN CAFFVNIAIL MLAASVFWKS NIQVTELSEA YRLLTKLMDG 
421:	KLAAVLFGLG LFLAGQSSTI TGTMAGQIVM EGFIKLRIKP WLRRFITRLL AIIPAAIVII 
481:	VLGDKGTYTL LIISQVLLSI GLPFAVVPLI IFTSSYEIMG EFKNRLSIII INSIIALFII 
541:	GLNLATIFQL INDFLHNDSI ISKCLTIIFL IPLSIALCCL LLWLIISKIN FFTNLLSKIF 
601:	NNNNNNNNKN IINNNNNYSG NTINNQTIQ