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2.A.55.2.13

Enterocyte iron uptake system, NRAMP or DMT1 of 558 aas and 13 TMSs.  Inhibited by lead and cadmium ions competitively (Kwong et al. 2010). The close (85% identity) homologue from Scophthalmus maximus (Turbot) (Psetta maxima) has been characterized (Chen et al. 2007).

Accession Number:Q9W666
Protein Name:Natural resistance associated macrophage protein-beta
Length:558
Molecular Weight:61639.00
Species:Oncorhynchus mykiss (Rainbow trout) [8022]
Number of TMSs:13
Substrate Fe2+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	METEREADLL EEEPPQENGV IQSTQGLYSS TSPPASDDEP FSTYFEEKVP IPEDVTQMFS 
61:	FRKLWAFTGP GFLMSIAYLD PGNIESDLQS GAKAGFKLLW VLLGATIIGL LLQRLAARLG 
121:	VVTGMHLAEV CNRQYPTVPR IILWLMVELA IIGSDMQEVI GCAIAFNLLS MGRIPLWGGV 
181:	LITIIDTFVF LFLDKYGLRK LEAFFGFLIT TMAVSFGYEY VMVRPDQGEL LKGMFLPYCE 
241:	NCDSAQMEQA VGIVGAVIMP HNIYLHSALV KSRQIDRGNK KEVKEANKYY FIESTIALFI 
301:	SFLINVFVVA VFAEAFYDKT NIEVNAKCNA SGSPHTDLFP LDNSTLQVDI LKGGVVLGCF 
361:	FGPAALYIWA IGILAAGQSS TMTGTYSGQF VMEGFLNLRW SRFARVLLTR SIAIFPTLLV 
421:	AIFQDVQHLT GMNDFLNVLQ SMQLPFALIP ILTFTSLTSI MDDFANGLVW KIGGGVVILV 
481:	VCAINMYFVV VYVTSLNSVA LYVLVALLCI AYLSFVCYLA WQCLIALGVS CLDVSCLGNR 
541:	VSNNCHAVFI EEQPAYDT