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2.A.55.2.8
Ethylene-insensitive protein 2 (AtEIN2) (EIN-2) (Cytokinin-resistant protein AtCKR1)

Accession Number:Q9S814
Protein Name:Ethylene-insensitive protein 2
Length:1294
Molecular Weight:140956.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: Q9S814
eggNOG: COG1914
HEGENOM: HOG000084434
Entrez Gene ID: 831889   
Pfam: PF01566   
KEGG: ath:AT5G03280   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0009734 P:auxin mediated signaling pathway
GO:0009926 P:auxin polar transport
GO:0071281 P:cellular response to iron ion
GO:0009736 P:cytokinin mediated signaling pathway
GO:0052544 P:defense response by callose deposition in cell wall
GO:0042742 P:defense response to bacterium
GO:0050832 P:defense response to fungus
GO:0001736 P:establishment of planar polarity
GO:0009871 P:jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway
GO:0010150 P:leaf senescence
GO:0031348 P:negative regulation of defense response
GO:0009789 P:positive regulation of abscisic acid mediated signaling pathway
GO:0010119 P:regulation of stomatal movement
GO:0009408 P:response to heat
GO:0002237 P:response to molecule of bacterial origin
GO:0009651 P:response to salt stress
GO:0048765 P:root hair cell differentiation
GO:0010182 P:sugar mediated signaling pathway

References (9)

[1] “EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis.”  Alonso J.M.et.al.   10381874
[2] “Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence features of the 1.6 Mb regions covered by twenty physically assigned P1 clones.”  Sato S.et.al.   9330910
[3] “Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.”  Tabata S.et.al.   11130714
[4] “Cytokinin action is coupled to ethylene in its effects on the inhibition of root and hypocotyl elongation in Arabidopsis thaliana seedlings.”  Cary A.J.et.al.   7770519
[5] “Identification of three genetic loci controlling leaf senescence in Arabidopsis thaliana.”  Oh S.A.et.al.   9351240
[6] “Analysis of combinatorial loss-of-function mutants in the Arabidopsis ethylene receptors reveals that the ers1 etr1 double mutant has severe developmental defects that are EIN2 dependent.”  Hall A.E.et.al.   12953109
[7] “Transcriptome analysis of O3-exposed Arabidopsis reveals that multiple signal pathways act mutually antagonistically to induce gene expression.”  Tamaoki M.et.al.   15010611
[8] “Growth regulators and the control of nucleotide sugar flux.”  Seifert G.J.et.al.   14973160
[9] “Transcriptional profiling by cDNA-AFLP and microarray analysis reveals novel insights into the early response to ethylene in Arabidopsis.”  De Paepe A.et.al.   15272873

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
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  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEAEIVNVRP QLGFIQRMVP ALLPVLLVSV GYIDPGKWVA NIEGGARFGY DLVAITLLFN 
61:	FAAILCQYVA ARISVVTGKH LAQICNEEYD KWTCMFLGIQ AEFSAILLDL TMVVGVAHAL 
121:	NLLFGVELST GVFLAAMDAF LFPVFASFLE NGMANTVSIY SAGLVLLLYV SGVLLSQSEI 
181:	PLSMNGVLTR LNGESAFALM GLLGASIVPH NFYIHSYFAG ESTSSSDVDK SSLCQDHLFA 
241:	IFGVFSGLSL VNYVLMNAAA NVFHSTGLVV LTFHDALSLM EQVFMSPLIP VVFLMLLFFS 
301:	SQITALAWAF GGEVVLHDFL KIEIPAWLHR ATIRILAVAP ALYCVWTSGA DGIYQLLIFT 
361:	QVLVAMMLPC SVIPLFRIAS SRQIMGVHKI PQVGEFLALT TFLGFLGLNV VFVVEMVFGS 
421:	SDWAGGLRWN TVMGTSIQYT TLLVSSCASL CLILWLAATP LKSASNRAEA QIWNMDAQNA 
481:	LSYPSVQEEE IERTETRRNE DESIVRLESR VKDQLDTTSV TSSVYDLPEN ILMTDQEIRS 
541:	SPPEERELDV KYSTSQVSSL KEDSDVKEQS VLQSTVVNEV SDKDLIVETK MAKIEPMSPV 
601:	EKIVSMENNS KFIEKDVEGV SWETEEATKA APTSNFTVGS DGPPSFRSLS GEGGSGTGSL 
661:	SRLQGLGRAA RRHLSAILDE FWGHLYDFHG QLVAEARAKK LDQLFGTDQK SASSMKADSF 
721:	GKDISSGYCM SPTAKGMDSQ MTSSLYDSLK QQRTPGSIDS LYGLQRGSSP SPLVNRMQML 
781:	GAYGNTTNNN NAYELSERRY SSLRAPSSSE GWEHQQPATV HGYQMKSYVD NLAKERLEAL 
841:	QSRGEIPTSR SMALGTLSYT QQLALALKQK SQNGLTPGPA PGFENFAGSR SISRQSERSY 
901:	YGVPSSGNTD TVGAAVANEK KYSSMPDISG LSMSARNMHL PNNKSGYWDP SSGGGGYGAS 
961:	YGRLSNESSL YSNLGSRVGV PSTYDDISQS RGGYRDAYSL PQSATTGTGS LWSRQPFEQF 
1021:	GVAERNGAVG EELRNRSNPI NIDNNASSNV DAEAKLLQSF RHCILKLIKL EGSEWLFGQS 
1081:	DGVDEELIDR VAAREKFIYE AEAREINQVG HMGEPLISSV PNCGDGCVWR ADLIVSFGVW 
1141:	CIHRVLDLSL MESRPELWGK YTYVLNRLQG VIDPAFSKLR TPMTPCFCLQ IPASHQRASP 
1201:	TSANGMLPPA AKPAKGKCTT AVTLLDLIKD VEMAISCRKG RTGTAAGDVA FPKGKENLAS 
1261:	VLKRYKRRLS NKPVGMNQDG PGSRKNVTAY GSLG