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2.A.57.1.2
Equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter of 456 aas, ENT2 (Slc29a2).  In humans, the same gene product is the nucleolar protein, HNP36 (function unknown).

Accession Number:Q61672
Protein Name:ENT2 aka HNP36 aka SLC29A2 aka DER12
Length:327
Molecular Weight:36114.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Nucleus membrane1 / Multi-pass membrane protein2
Substrate Nucleosides

Cross database links:

Genevestigator: Q61672
eggNOG: roNOG11626
Pfam: PF01733   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0031965 C:nuclear membrane
GO:0005337 F:nucleoside transmembrane transporter activity
GO:0006810 P:transport

References (1)

[1] “A mammalian delayed-early response gene encodes HNP36, a novel, conserved nucleolar protein.”  Williams J.B.et.al.   7639753

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MASVWFINSF CAVLQGSLFG QLGTMPSTYS TLFLSGQGLA GIFAALAMLM SLASGVDAQT 
61:	SALGYFITPC VGILLSIVCY LSLPHLKFAR YYLTEKLSQA PTQELETKAE LLQADEKNGV 
121:	PISPQQASPT LDLDPEKEPE PEEPQKPGKP SVFVVFRKIW LTALCLVLVF TVTLSVFPAI 
181:	TAMVTTSSNS PGKWGLFFNP ICCFLLFNVM DWLGRSLTSY FLWPDEDSQQ LLPLLVCLRF 
241:	LFVPLFMLCH VPQHARLPII FRQDAYFITF MLLFAVSNGY LVSLTMCLAP RQVLPHEREV 
301:	AGALMTFFLA LGLSCGASLS FLFKALL