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2.A.57.2.8
Nucleotide transporter 2, NT2, specific for inosine and guanosine, but mutations in TMS 4 which may line the channel allow uptake of adenosine (Arendt & Ullman et al., 2010). (Most similar to 2.A.57.2.3).

Accession Number:Q9GTP4
Protein Name:Nucleoside transporter 2
Length:502
Molecular Weight:54874.00
Species:Crithidia fasciculata [5656]
Number of TMSs:11
Substrate Inosine, Guanosine

Cross database links:

Pfam: PF01733   

Gene Ontology

GO:0016020 C:membrane
GO:0005337 F:nucleoside transmembrane transporter activity

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTTSSDSAMV NHTPSPWYKF GFKSFAEFNT YVTFVFLGMS IMMVASAVTS APDFLTRYYV 
61:	YATGDPDAVA ETPLFWNNAN TFYNAGTYVL QVLTELFSLT PFMRRIPLSV RLFVGLGIPF 
121:	AELLLIIIVP AATIKSQHGA IAVIMVVACV GGFSKALCDS CTNALVGPFP TKFMNGAQWG 
181:	LTVIALLMSI IQIILKVSMG TSFHDILTMS RIYFGICIGI QLFAIFELAI LRFNPFAQKY 
241:	IAEYRAGAQR NAQNNESTLE ETAPSMNEPA AGDIADLPAT VDDKERALNE EEGDEVRAVT 
301:	SEEFHVKRGA VLTATGDADK MVDLDQTGNI TSTEQLLRAS AASVFKRVYP MLVCVFLIYF 
361:	TSLLTFPGVF FLVSTTSGWY MTVIVTLFNA GDFISRMVLM FRPLRPSPKV VVAGTLGRLI 
421:	IIPFLVLCVR GIIRGEALPY VLITLLGLTN GYFGCMACIH CPRTTTLRYA GERSLAAMLS 
481:	GISIMLGLCF GSNLSLAITL TH