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2.A.6.2.36
Multidrug/detergent exporter.  VexB (Bina et al., 2008b).

Accession Number:Q9KVI2
Protein Name:Multidrug resistance protein, putative
Length:1036
Molecular Weight:111811.00
Species:Vibrio cholerae [666]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Secreted1
Substrate drugs, detergents

Cross database links:

HEGENOM: HBG293864
RefSeq: NP_229821.1   
Entrez Gene ID: 2612953   
Pfam: PF00873   
KEGG: vch:VC0164   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.”  Heidelberg J.F.et.al.   10952301

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MRFTDVFIKR PVLAVSISFL IVLLGLQAIF KMQVREYPEM TNTVITVSTG YYGASADLIQ 
61:	GFITQPLEQA VAQADNIDFM TSQSVLGRST ITVTMKLNTD PNAALSDVLA KTNSVRSQLP 
121:	KEAEDPTVTM STGSTTAVLY IGFTSNELAS SQITDYLERV VNPQLYAVNG VSSIDLYGGM 
181:	KYALRVWLDP AKMAALNLSA ADVMSILNAN NYQSATGQAI GEFVLYNGSA DTQVSTVEDL 
241:	ESLVVKAEKG TVTRLGDIAK VTLAKSHDTY RASANGREAV VAAINAAPSA NPINIAKDVL 
301:	EMLPELQKNM PSNIEMNVLY DSTVAINESI HEVIKTIVEA ALIVLVVITL FLGSLRAVLI 
361:	PIVTIPLSLI GVAMVMQMMG FSWNLMTLLA MVLAIGLVVD DAIVVLENVD RHIKEGESPF 
421:	RAAIIGTREI AIPVIAMTLT LGAVYAPIAL MGGITGSLFK EFALTLAGSV FVSGIVALTL 
481:	SPMMCSKMLK ANEAPNKFEL KVHHLLDRMT ARYERMLTAV MAHRPVVIAF AFIVFASLPM 
541:	LFKFIPSELA PSEDKGVIML MGTGPSNANL DYLANTMDDV NKILSDQPEV QFAQVFTGVP 
601:	NSNQAFGIAS MVPWSQREAS QATVTNRVGT LVQDIPGMAV TAFQMPELPG AGSGLPIQFV 
661:	ITTPSNFESL FTIATDVLTE VKANPMFVYS DLDLNFDSAT MKINIDKDKA GAYGVTMQDI 
721:	GITLSTMMAD GYVNRIDLNG RSYEVIPQVE RKWRLNPESM NSYYVRAADG KVIPLGSLVT 
781:	IDVVAEPRSL PHFNQLNSAT VGAVPAPGTA MGDAINWFEN LASSKLPKGY SHDYMGEARQ 
841:	YVTEGSALYA TFGLALAIIF LVLAIQFESL RDPLVIMVSV PLAICGALIA LAWGTATMNI 
901:	YSQVGLITLV GLITKHGILI CEVAKEEQLH NKLSRIEAVM HAAKVRLRPI LMTTAAMIAG 
961:	LIPLMYATGA GAAQRFSIGI VIVSGLAIGT LFTLFVLPVI YSYLAEKHKP LPVFVEDKDL 
1021:	EKLARIDEAK AAHRQL