TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.6.5.1
The antibiotic actinorhodin transport-associated protein, ActII3

Accession Number:Q53902
Protein Name:MMLA aka ActII3 aka SCO5084 aka SCBAC28G1.10
Length:711
Molecular Weight:74863.00
Species:Streptomyces coelicolor [1902]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Actinorhodin

Cross database links:

HEGENOM: HBG579768
RefSeq: NP_629234.1   
Entrez Gene ID: 1100525   
BioCyc: SCOE100226:SCO5084-MONOMER   
KEGG: sco:SCO5084   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (2)

[1] “The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces.”  Fernandez-Moreno M.A.et.al.   1878971
[2] “Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).”  Bentley S.D.et.al.   12000953

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MTRTLLSWPG GRRLKWLVLA AWIGLLIVLQ PLAGKLGDVE SNDAAAWLPG NAESTEVLEL 
61:	SEKFQPADTS PTVIVYDRPS GITAADEAKA RADATHFADG TGVVGEPYGP VRSDDGKALR 
121:	TVVNVHLGKD GWEGLNAAAK DMRAIARPSA PDGLGVHVTG PTGYAADSAE SFSSADFKLT 
181:	LVTLLIVVTI LVVTYRSPLL WLLPMISAGM SLVISQAIVY LLAKNAGLTV NAQTAMILTV 
241:	LVLGAATDYA LLLVARYREE LRRHEDRHEA MAVALRRAGP AIVASAATVA VSMLVLLLAA 
301:	LNSTKGLGPV CAVGVLVGLL SMMTLLPALL VIFGRWVFWP ARPKHGTEPD VTRGLWSRIA 
361:	RLVSGRPRAV WVTTSLLLGA VATLAVTLNA DGLQQKDGFK TKPESVVGEE ILTRHFPAGS 
421:	GEPMVVIAKG ASADQVHAAL ETVPGVIEVA PPQVKDGLAY VEATLGAGAD SPAAMRSVTA 
481:	ARETLARLDG AQARVGGSSA VVHDMREASS RDRGLIIPVI LAVVFCILAL LLRALVAPLL 
541:	LIASVVLSFF TALGLAALFF NHVFDFAGAD SAFPLWVFVF LVALGVDYNI FLVTRIKEES 
601:	DRLGTRQGAL KGLTSTGGVI TAAGLVLAGT FAALATLPLV FIAELGFTVA VGVLLDTMIV 
661:	RSVLVTALTL DVGRWMWWPH PLARREDPSE DPAVSGMPDS IDSEASTTAS R