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2.A.6.5.13
Lipid (acyl and diacyl trehalose) exporter of 1002 aas and 12 TMSs, MmpL10 (Bailo et al. 2015). A 12 TMS topology has been determined (Belardinelli and Jackson 2017).

Accession Number:P9WJU1
Protein Name:Acyltrehalose exporter MmpL10
Length:1002
Molecular Weight:106415.00
Species:Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [83332]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate acyl trehalose, diacyl trehalose

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVGCWVALAL VLPMAVPSLA EMAQRHPVAV LPADAPSSVA VRQMAEAFHE SGSENILVVL 
61:	LTDEKGLGAA DENVYHTLVD RLRNDAKDVV MLQDFLTTPP LREVLGSKDG KAWILPIGLA 
121:	GDLGTPKSYH AYTDVERIVK RTVAGTTLTA NVTGPAATVA DLTDAGARDR ASIELAIAVM 
181:	LLVILMVIYR NPVTMLLPLV TIGASLMTAQ ALVAGVSLVG GLAVSNQAIV LLSAMIAGAG 
241:	TDYAVFLISR YHEYVRLGEH PERAVQRAMM SVGKVIAASA ATVGITFLGM RFAKLGVFST 
301:	VGPALAIGIA VSFLAAVTLL PAILVLASPR GWVAPRGERM ATFWRRAGTR IVRRPKAYLG 
361:	ASLIGLVALA SCASLAHFNY DDRKQLPPSD PSSVGYAAME HHFSVNQTIP EYLIIHSAHD 
421:	LRTPRGLADL EQLAQRVSQI PGVAMVRGVT RPNGETLEQA RATYQAGQVG NRLGGASRMI 
481:	DERTGDLNRL ASGANLLADN LGDVRGQVSR AVAGVRSLVD ALAYIQNQFG GNKTFNEIDN 
541:	AARLVSNIHA LGDALQVNFD GIANSFDWLD SVVAALDTSP VCDSNPMCGN ARVQFHKLQT 
601:	ARDNGTLDKV VGLARQLQST RSPQTVSAVV NDLGRSLNSV VRSLKSLGLD NPDAARARLI 
661:	SMQNGANDLA SAGRQVADGV QMLVDQTKNM GIGLNQASAF LMAMGNDASQ PSMAGFNVPP 
721:	QVLKSEEFKK VAQAFISPDG HTVRYFIQTD LNPFSTAAMD QVNTIIDTAK GAQPNTSLAD 
781:	ASISMSGYPV MLRDIRDYYE RDMRLIVAVT VVVVILILMA LLRAIVAPLY LVGSVVISYM 
841:	SAIGLGVVVF QVFLGQELHW SVPGLAFVVL VAVGADYNML LASRLRDESA LGVRSSVIRT 
901:	VRCTGGVITA AGLIFAASMS GLLFSSIGTV VQGGFIIGVG ILIDTFVVRT ITVPAMATLL 
961:	GRASWWPGHP WQRCAPEEGQ MSARMSARTK TVFQAVADGS KR