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2.A.6.5.3
The putative glycopeptidolipid exporter, TmtpC (most similar to MmpL of M. leprae; implicated in sliding motility). May function with the MmpS4 protein of Mucobacterium smegmatis (A0QPN7) to form a scaffold for coupled biosynthesis and transport (Deshayes et al., 2010).

Accession Number:Q9KH53
Protein Name:TmtpC
Length:994
Molecular Weight:107590.00
Species:Mycobacterium smegmatis [1772]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Glycopeptidolipids

Cross database links:

Gene Ontology

GO:0016021 C:integral to membrane

References (1)

[1] “Genetic analysis of sliding motility in Mycobacterium smegmatis.”  Recht J.et.al.   10894747

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSTEQSGTEK ARRPFFARAV RTLSPFIIVG WLAVILVTTL AAVGGDWSAA IPALERVGEK 
61:	NSVSLMPQDA PSAKAMKHMG QKFEESDSDS FAMIVLEGQE PLGPDALDYY TGLISELRND 
121:	SKHVEHVQDL WGDRLTASSA QSADGKAAYV QLNLAGNQGT PLGDESVAAV RDLVARTPAP 
181:	EGVSVYVTGA APLVSDMQHS GNRSILKITA VTVVIIFAML LMVYRSVITV ILLLIMVGFE 
241:	VAAARGIVAF LGANEVFVLS TFAVNMLVFL AIAAGTDYGI FFFGRYQEAR AAGEDRETAY 
301:	YSMYRGVTPV VMASGLTIAG AIFCLTFTRL PYFHTMGVPC AIGMLAAVAV AVTLVPAGVA 
361:	LAGRIGWLEP KRKMRVRRWR GIGTAIVRWP APILVASLAV ALVGLLALPG YETSYNDRDY 
421:	IPADIPANAG FAAADRHFSQ ARMTPDILMV ESDHDMRNPT DFLVLNKIAK AIFKVRGVSR 
481:	VQGITRPEGT PIERTSIPFL LSLQSAGQVQ ATNFQKQRIG DMLKQVDDMN MMIGVMKTTY 
541:	GVLQELAATT HSLNGSTHEL RDVARDLRGS IAIFDDLLRP IRNYFYWEPH CYNIPICWSL 
601:	RSIFDAMDGV DRLNDELQVL VDNMDRLDAL VPELVAQFPE YIASMETFRE LTLTSYSTFS 
661:	GLLQQMDEQT EDVTAMGQAF DAAKNDDTFF LPPEVFDNPD FKRAMTSFLS PDGKAARFII 
721:	SHNGDPATPE GISRVDQMQT AAVEALKGTP LTDAQVYLAG TAPTAKDWKD GSTYDLLIAG 
781:	IAAMCLIFII MLIVTRSFIA ALVIVGTVVL SLGASFGLSV LLWQYILGIH LHWMVLAMSV 
841:	IILLAVGSDY NLLLVSRIKE EVGAGINTGI VRAMGGTGKV VTSAGLVFAG TMAAMVVSDL 
901:	RIIGQIGTTI GLGLLFDTMI VRSFMTPSIA ALLGRWFWWP QKVRPRPASA LLEPYGPRPL 
961:	VRALLEGPSG AASPGGPGGR LSDDDTPTGP MRTR