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2.A.60.1.13
Liver anion transporter OatP of the little skate (689aas) (Cai et al., 2002)

Accession Number:Q8UVG4
Protein Name:OatP
Length:689
Molecular Weight:74833.00
Species:Raja erinacea (Little skate) [7782]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Basal cell membrane1 / Multi-pass membrane protein2
Substrate anions

Cross database links:

Pfam: PF07648    PF03137   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “An evolutionarily ancient Oatp: insights into conserved functional domains of these proteins.”  Cai S.Y.et.al.   11897630

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MENPHKEKFD STTCPPPAKV KHSRFNNLKL FLVALSFLYL AKTLSGSYMK STITQMERRF 
61:	DIPSSVIGVV DGSFEIGNLL VIAFVSYFGS KFHRPRLIAI GSVIMSLGTF LIALPHFFMG 
121:	PYNYETAIKY STNSTSVTSQ CSSNSSGTGP DEISSVPLPG CEEEGGSPMW VYILIGNLLR 
181:	GIGETPTGPL GISYLDDHAT EDNASFYIGI LHTIALIGPL FGYLLGSYCA KIFVDIGFVD 
241:	LEKVTISSKD ARWVGAWWLG FLIAGTVSIL TSIPFWFFPK SLTKKANKKE PSKVCEKMEF 
301:	IKQGQSEPAN AVISTKSKGF MVSVKLLFSN RIYVLYLLSM VVQINSLIGM LTFKAKFIEQ 
361:	QYGQSASRSN FIIGVINIPA VCLGIFLGGL VMKKFKLNVV QAAKFSVSCT CLGWLLSLSY 
421:	FGMGCDNSRV AGLTVSYEGN PQISFEGSGL YHGCNNKCSC SGSQWEPVCA DSGVTYVSPC 
481:	LAGCKTSSGV GKSTEFHNCS CISALISTNS SALLGQCAKA EDCEQIFPYY LVVTVLSAFS 
541:	YSFGAVPGFM ILLRCNEPEL KSLAIGIQTL IVRTLAGIPA PIYFGALIDQ TCLKWGAKRC 
601:	GGQGACRIYD SNAFRHIFLG LQAGLRGLGI IVFFHIVVLL QRQLRAKEKH AAPKGDNDVV 
661:	PMQDKDCGPE NGDITTKVNA NHPESESHV