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2.A.60.1.17
solute carrier organic anion transporter family, member 6A1

Accession Number:Q86UG4
Protein Name:Solute carrier organic anion transporter family member 6A1
Length:719
Molecular Weight:79232.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Organoanions

Cross database links:

Genevestigator: Q86UG4 Q86UG4
eggNOG: NOG257460 NOG257460
HEGENOM: HOG000231270 HOG000231270
Entrez Gene ID: 133482   
Pfam: PF07648    PF03137   
KEGG: hsa:133482    hsa:133482   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity

References (10)

[1] “Identification and characterization of novel rat and human gonad-specific organic anion transporters.”  Suzuki T.et.al.   12677006
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The DNA sequence and comparative analysis of human chromosome 5.”  Schmutz J.et.al.   15372022
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[5] “Identification of the gonad-specific anion transporter SLCO6A1 as a cancer/testis (CT) antigen expressed in human lung cancer.”  Lee S.-Y.et.al.   15546177
[6] “Identification and characterization of novel rat and human gonad-specific organic anion transporters.”  Suzuki T.et.al.   12677006
[7] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[8] “The DNA sequence and comparative analysis of human chromosome 5.”  Schmutz J.et.al.   15372022
[9] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[10] “Identification of the gonad-specific anion transporter SLCO6A1 as a cancer/testis (CT) antigen expressed in human lung cancer.”  Lee S.-Y.et.al.   15546177

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFVGVARHSG SQDEVSRGVE PLEAARAQPA KDRRAKGTPK SSKPGKKHRY LRLLPEALIR 
61:	FGGFRKRKKA KSSVSKKPGE VDDSLEQPCG LGCLVSTCCE CCNNIRCFMI FYCILLICQG 
121:	VVFGLIDVSI GDFQKEYQLK TIEKLALEKS YDISSGLVAI FIAFYGDRKK VIWFVASSFL 
181:	IGLGSLLCAF PSINEENKQS KVGIEDICEE IKVVSGCQSS GISFQSKYLS FFILGQTVQG 
241:	IAGMPLYILG ITFIDENVAT HSAGIYLGIA ECTSMIGYAL GYVLGAPLVK VPENTTSATN 
301:	TTVNNGSPEW LWTWWINFLF AAVVAWCTLI PLSCFPNNMP GSTRIKARKR KQLHFFDSRL 
361:	KDLKLGTNIK DLCAALWILM KNPVLICLAL SKATEYLVII GASEFLPIYL ENQFILTPTV 
421:	ATTLAGLVLI PGGALGQLLG GVIVSTLEMS CKALMRFIMV TSVISLILLV FIIFVRCNPV 
481:	QFAGINEDYD GTGKLGNLTA PCNEKCRCSS SIYSSICGRD DIEYFSPCFA GCTYSKAQNQ 
541:	KKMYYNCSCI KEGLITADAE GDFIDARPGK CDAKCYKLPL FIAFIFSTLI FSGFSGVPIV 
601:	LAMTRVVPDK LRSLALGVSY VILRIFGTIP GPSIFKMSGE TSCILRDVNK CGHTGRCWIY 
661:	NKTKMAFLLV GICFLCKLCT IIFTTIAFFI YKRRLNENTD FPDVTVKNPK VKKKEETDL