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2.A.60.1.28
Thyroid hormone transporter, OATP1C1, of 710 aas and 12 TMSs in a clear 3 + 3 + 3 + 3 arrangement (Zada et al. 2017).

Accession Number:B3DJD4
Protein Name:Solute carrier organic anion transporter family member
Length:710
Molecular Weight:78083.00
Species:Danio rerio (Zebrafish) [7955]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Thyroid hormones

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPRNCMKESS SPKENEIFLW RMDLPNKERR SPENSPSSSR RCCSSFKMFL VALSFAYFSK 
61:	ALSGSYMKST ITQLERRFDI PSYLIGVIDG SFEIGNLLVI AFVSYFGAKL HRPKIIAIGC 
121:	LLMSLGTFLI ALPHFIIGRY KFETSIRLSV NSSSSLSPCS LSSAEPSTSS VPSTGCEHES 
181:	RLSMWIYVFL GNILRGIGET PVQPLGISYI DDHALEENAA FYIGCVQTIS VIGPVFGYLL 
241:	GSVCAKIYVD IGFVNMESIS ITPGDARWVG AWWLGYLIAG FITLLSAVPF WFLPKSLPLP 
301:	ERRLSKYSPE RNSFIKDSAL LEHKYQADEP ANFLEMAKDF LPTLRSLLGN PVYFLYLCVT 
361:	IIQFNSLIGM VTYKPKYIEQ HYGQSASKAN FLMGVINIPA VALGMFSGGV IMKKFKLSIM 
421:	GAAKFALGTS LLGYFLSLFF FSMGCENASV AGITMSYNGT ESLFMADGSL RASCNAACHC 
481:	PEKNWDPVCG EDGLTYVSPC LAGCRTSHGS GMDTVFEQCS CIGVGNQTAT AGQCNNRESC 
541:	HRIFPYFLAL SVITSFIISL GGTPGYMLLI RCIKPQLKSL ALGFHTLTTR TLAGIPAPIY 
601:	FGAIIDTTCL KWGHKKCGGR GACRIYNTAA YRIAYLGLTL GLRTVSFFLC ILGLLVLRRH 
661:	VQKQERSTMV NGGSAAAGEL QALRKEENNS CNSEQCPQNT DYDPERETRL