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2.A.60.1.29
LST-3TM12 (LST3; SLCO1B7 is a product of splicing of SLCO1B3 and SLCO1B7, and encodes a protein with 640 aas and 12 TMSs. LST-3TM12 mRNA was verified by polymerase chain reaction showing liver enriched expression (Malagnino et al. 2017). LST-3TM12 is expressed in the PM and ER of hepatocytes and is associated with enhanced cellular accumulation of dehydroepiandrosterone sulfate (Vmax 300 pmol/mg/min; Km 34 µM) and estradiol 17-beta-glucuronide (Vmax 30 µmol/ mg/min; Km 33 µM) (Malagnino et al. 2017).

Accession Number:G3V0H7
Protein Name:Putative solute carrier organic anion transporter family member 1B7
Length:640
Molecular Weight:71247.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKISTTQIER RFEISSSLVG LIDGSFEIGN LFVIVFVSYF GSKLHRPKLI GIGCFLMGTG 
61:	SILMALPHFF MGYYRYSKET NIDPSENSTS NLPNCLINQM LSLNRTPSEI IERGCVKESG 
121:	SHMWIYVFMG NMLRGIGETP IVPLGISYID DFAKEGHSSL YLGTVNVMGM TGLVFAFMLG 
181:	SLFAKMYVDI GYVDLSTIRI TPKDSRWVGA WWLGFLVSGI VSIISSIPFF FLPLNPNKPQ 
241:	KERKVSLFLH VLKTNDKRNQ IANLTNRRKY ITKNVTGFFQ SLKSILTNPL YVIFVIFTLL 
301:	HMSSYIASLT YIIKMVEQQY GWSASKTNFL LGVLALPAVA IGMFSGGYII KKFKLSLVGL 
361:	AKLAFCSATV HLLSQVLYFF LICESKSVAG LTLTYDGNSP VRSHVDVPLS YCNSECNCDE 
421:	SQWEPVCGNN GITYLSPCLA GCKSSSGNKE PIVFYNCSCV EVIGLQNKNY SAHLGECPRD 
481:	DACTRKSYVY FVIQVLDAFL CAVGLTSYSV LVIRIVQPEL KALAIGFHSM IMRSLGGILV 
541:	PIYFGALIDT TCMKWSTNSC GARGACRIYN STYLGRAFFG LKVALIFPVL VLLTVFIFVV 
601:	RKKSHGKDTK VLENERQVMD EANLEFLNDS EHFVPSAEEQ