TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*2.A.63.1.1









Multicomponent K+:H+ antiporter, PhaABCDEFG. Can also transport Na+ (Yamaguchi et al., 2009).

Bacteria
Proteobacteria
PhaABCDEFG of Sinorhizobium meliloti
*2.A.63.1.2









Multicomponent Na+:H+ antiporter, NhaA-G. Nha1,2,3,(4)

Bacteria
Firmicutes
NhaA-G of Bacillus halodurans (strain C-125)
NhaA (804 aas)(Q7AJV8)
NhaB (146 aas)(Q7AJV9)
NhaC (112 aas)(Q7AJW0)
NhaD (493 aas)(Q9KD98)
NhaE (158 aas)(Q9KD99)
NhaF (95 aas)(Q9KDA0)
NhaG (117 aas)(Q9KDA1) 
*2.A.63.1.3









Multicomponent Na+:H+ antiporter, MnhABCDEFG
Bacteria
Firmicutes
MnhABCDEFG of Staphylococcus aureus
*2.A.63.1.4









Multicomponent Na+:H+ antiporter, MrpA-G (ShaA-G) (all components comprise a multi-component complex) (Kajiyama et al., 2007; Morino et al., 2008). The MrpA, MrpB, and MrpD subunits contain membrane-embedded and essential acidic residues (Kajiyama et al. 2009). Several residues important for Na+/H+ antiport activity, sodium exclusion, individual Mrp protein levels, or Mrp complex formation have been identified (Morino et al., 2010).

Bacteria
Firmicutes
MrpA-G of Bacillus subtilis
MrpA (801 aas; Q9K2S2)
MrpB (143 aas; O05259)
MrpC (113 aas; O05260)
MrpD (493 aas; O05229)
MrpE (158 aas; Q7WY60)
MrpF (94 aas; O05228)
MrpG (124 aas; O05227)
*2.A.63.1.5









Bacteria
Actinobacteria
Putative membrane protein of Streptomyces coelicolor
*2.A.63.2.1









The Na+:H+ antiporter, MrpA-G complex. Catalyzes Na+:H+ and Li+:H+ antiport. The MrpB subunit may have this transport activity by itself (Fukaya et al., 2009).

Bacteria
Cyanobacteria
MrpA-G of Aphanothece halophytica
MrpA (C7G3J5)
MrpB (C7G3J6)
MrpC (C7G3I9)
MrpD1 (C7G3J0)
MrpD2 (C7G3J1)
MrpE (C7G3J2)
MrpF (C7G3J3)
MrpG (C7G3J4)