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2.A.66.1.25
Probable multidrug resistance protein YoeA

Accession Number:O34474
Protein Name:Probable multidrug resistance protein yoeA
Length:463
Molecular Weight:51305.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate drugs

Cross database links:

eggNOG: COG0534
HEGENOM: HOG000072914
Entrez Gene ID: 939596   
Pfam: PF01554   
KEGG: bsu:BSU18370   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015297 F:antiporter activity
GO:0015238 F:drug transmembrane transporter activity
GO:0006811 P:ion transport

References (2)

[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[2] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	METSQEPLVT QKKSKPSVWR SMSLFLVPLL LSNVLQSVGQ LVGMMAVGRW LGVDAVAAVS 
61:	SFFPLFFLLI SFTIGIGSGS SILIGQAYGA KNEERLKAVV GTTLTFTFLL GVVLAVIGSI 
121:	FTLDILRLMG TPENVIHVSA NYARILFYAM PFMFLYFAYT TFLRGTGDSK TPFYTLIVST 
181:	VINIALLPVL ILGMFGFPKL GIYGSAYATV ISTIATFLVL MVYLRKRKHP LQFDKTVRRY 
241:	LKMDKELLVL LLRLGVPASI NMILVSLSEI AVISFVNHYG SNATAAYGVV NQVASYVQMP 
301:	AVSLGIAVSI FAAQSIGANE FDRLKQVIRV GIWLNYIIGG VLIILIYVFS HQILSLFLTE 
361:	QETLYIAHRL LMITLWSYLL FGNAQIISAT MRASGTVLWP TVISIFAIWG VEVPVAFVLS 
421:	HYTKLEILGV WVGYPAAFAV SLLLIYGYYQ FVWKKKQITR LIQ