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2.A.66.1.27
Probable multidrug resistance protein NorM (Multidrug-efflux transporter)

Accession Number:P58163
Protein Name:Probable multidrug resistance protein NorM
Length:471
Molecular Weight:49531.00
Species:Caulobacter crescentus (strain ATCC 19089 / CB15) [190650]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate drugs

Cross database links:

eggNOG: COG0534
HEGENOM: HOG000041540
Entrez Gene ID: 942799   
Pfam: PF01554   
KEGG: ccr:CC_2020   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015297 F:antiporter activity
GO:0015238 F:drug transmembrane transporter activity
GO:0006811 P:ion transport

References (1)

[1] “Complete genome sequence of Caulobacter crescentus.”  Nierman W.C.et.al.   11259647

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTVVTTMPRD AAGTALLPER PRGPIMTDLI ELLRLAGPVV LSRLGIMVMG LTDAIVVGHF 
61:	SAQQLGYHAM AWAPSSVFVT ATVGLLVGVQ VMTARAMGAG NPHETGAVLR RGLVYAGWLG 
121:	FGSMALLALF GPMFLQAMGL KDGLAEGATL PLIVFSLSLP VYAISVVLTF WLEGLSRPGP 
181:	GAAMMWLANV VNLGANLLLV PGVLGPPALG AVGGAWATFI ARTALALALA IFVIRMKEAR 
241:	ELGVFDKPAR DRPAEIEQRR IGYGAGASNF FEVSAFAGMN LICGWISAVA VAAYTVVLNV 
301:	SAIIFMVPLG VASATAVMVG RAYGARDPAG MTRAGWIAFA VIGVIGVLFG LLLYPTKHWV 
361:	ALAYTTDPAA LALILPALVL ACLFFAPDAV QVVAAQALRA RGEVWVPTIT HLISYALVMG 
421:	PLAWWLAIPK GMGLNGVLVS IIVTSFLAAG FLLMRFRMLD WRDRKAAQEA A