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2.A.66.1.41
Na+-coupled multidrug efflux pump, PdrM (Hashimoto et al. 2013). Confers resistance to several antibacterial agents including norfloxacin, acriflavine, and 4',6-diamidino-2-phenylindole (DAPI).

Accession Number:Q8DPQ6
Protein Name:Probable multidrug resistance protein NorM
Length:453
Molecular Weight:50061.00
Species:Streptococcus pneumoniae (strain ATCC BAA-255 / R6) [171101]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Na+, norfloxacin, acriflavine, DAPI

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  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MYKTKCLREK LVLFLKIFFP ILIYQFANYS ASFVDTAMTG QYNTMDLAGV SMATSIWNPF 
61:	FTFLTGIVSA LVPIIGHHLG RGKKEEVASD FYQFIYLALG LSVVLLGMVL FLAPTILNHI 
121:	GLEAAVAAVA VRYLWFLSIG IIPLLLFSVI RSLLDSLGLT KLSMYLMLLL LPLNSGFNYL 
181:	LIYGAFGVPE LGGAGAGLGT SLAYWVLLGI SVLVLFKQEK LKALHLEKRI LLNMDKIKEG 
241:	VRLGLPIGGT VFAEVAVFSV VGLIMAKFSS LIIASHQSAM NFSSLMYAFP MSISSAMAIV 
301:	VSYEVGAKRF DDAKTYIGLG RWTALIFAAF TLTFLYIFRG NVASLYGNDP KFIDLTARFL 
361:	TYSLFFQLAD TFAAPLQGIL RGYKDTVIPF YLGLLGYWGV AIPVATLFDS LTDFGAYSYW 
421:	IGLIISLIVS GALYRWRLTV IMKRFESLAK SKR