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2.A.66.1.51
Multidrug resistance efflux pump, Detoxification 48, DTX48. Functions as a multidrug and toxin extrusion transporter. Contributes to iron homeostasis during stress responses and senescence (Seo et al. 2012). Overexpression of DTX48 alters shoot developmental programs leading to a loss of apical dominance phenotype (Wang et al. 2015).

Accession Number:Q9SLV0
Protein Name:Protein DETOXIFICATION 48
Length:532
Molecular Weight:57847.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MCNSKPSSAS SSLLSCKDKT HISKLETCDT DNPHYSEFRD TDSLDLKRWP SFLEGLEEVK 
61:	AIGKISGPTA MTGLLMYSRA MISMLFLGYL GELELAGGSL SIGFANITGY SVISGLSMGM 
121:	EPICGQAYGA KQMKLLGLTL QRTVLLLLSC SVPISFSWLN MRRILLWCGQ DEEISSVAQQ 
181:	FLLFAIPDLF LLSLLHPLRI YLRTQNITLP VTYSTAVSVL LHVPLNYLLV VKLEMGVAGV 
241:	AIAMVLTNLN LVVLLSSFVY FTSVHSDTWV PITIDSLKGW SALLSLAIPT CVSVCLEWWW 
301:	YEFMIILCGL LANPRATVAS MGILIQTTAL VYVFPSSLSL GVSTRISNEL GAKRPAKARV 
361:	SMIISLFCAI ALGLMAMVFA VLVRHHWGRL FTTDAEILQL TSIALPIVGL CELGNCPQTT 
421:	GCGVLRGCAR PTLGANINLG SFYFVGMPVA ILFGFVFKQG FPGLWFGLLA AQATCASLML 
481:	CALLRTDWKV QAERAEELTS QTPGKSPPLL PIASSKSRST SGTEDMMRTM LV