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2.A.66.2.14
The 14 TMS SpoVB protein (possibly catalyzes lipid-linked oligosaccharide transport across the cytoplasmic membrane; required for proper cell wall biosynthesis) (Vasudevan et al., 2009).

Accession Number:Q00758
Protein Name:Stage V sporulation protein B
Length:518
Molecular Weight:56079.00
Species:Bacillus subtilis [1423]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Lipid-linked oligosaccharides

Cross database links:

HEGENOM: HBG712836
RefSeq: NP_390645.1   
Entrez Gene ID: 938022   
Pfam: PF01943   
KEGG: bsu:BSU27670   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015297 F:antiporter activity
GO:0015238 F:drug transmembrane transporter activity
GO:0006855 P:drug transmembrane transport
GO:0000271 P:polysaccharide biosynthetic process
GO:0030435 P:sporulation resulting in formation of a cel...

References (2)

[1] “Cloning, characterization, and expression of the spoVB gene of Bacillus subtilis.”  Popham D.L.et.al.   1744050
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAKQTFLKGT LILIAAGMVT RMLGFVNRVV IARFIGEEGV GLYMMAAPTF FLATTLTQFG 
61:	LPVAISKLVA EASARGDHQK TKNILVMSLT ITGVLSLIFT PLFLFFAPVM AETMLTDKRT 
121:	LYPLLAITPV VPIIAISSVL RGYFQGKQNM NPLAMSQVLE QVVRISLVAV CTTIFLPYGI 
181:	EYAAAGAMLS SVAGELASLL YLFVCFKYKK TIKIRKHFLQ SIKNGKQTFT QLMSVSLPTT 
241:	GSRFIGNLSW FFEPIVVAQS LAIAGVATVA ATKQYGELTG FAMTLLTLPS FITYSLSTAL 
301:	VPAISEGMEQ KKLQVVEYRL EQAMRLCLLS GGISVVILFV FADELMRVMY GSSGAAVFIK 
361:	VMAPFFLLYY FQGPLQAVLQ ALNLAGAAMM NSLIGALVKT GLIFVLATRP SLGIMGAALA 
421:	IVTGMVLVTL LHAATVSKVL PISIKIKEYA LSFAVIVICG FISSAIKQYI SFGASEAVNL 
481:	AGWIAASAAI YMILLLVFRL IKKDELRRIP IIGRLIIR