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2.A.66.2.2
Probable succinoglycan exporter

Accession Number:P33699
Protein Name:ExoT aka RB1074 aka SMB20950
Length:494
Molecular Weight:53316.00
Species:Rhizobium meliloti (Sinorhizobium meliloti) [382]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Succinoglycan

Cross database links:

HEGENOM: HBG300100
RefSeq: NP_437614.1   
Entrez Gene ID: 1237405   
Pfam: PF01943   
BioCyc: SMEL266834:SMB20950-MONOMER   
KEGG: sme:SM_b20950   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0000271 P:polysaccharide biosynthetic process

References (4)

[1] “Family of glycosyl transferases needed for the synthesis of succinoglycan by Rhizobium meliloti.”  Glucksmann M.A.et.al.   8226645
[2] “Genes needed for the modification, polymerization, export, and processing of succinoglycan by Rhizobium meliloti: a model for succinoglycan biosynthesis.”  Glucksmann M.A.et.al.   8226646
[3] “Analysis of the Rhizobium meliloti genes exoU, exoV, exoW, exoT, and exoI involved in exopolysaccharide biosynthesis and nodule invasion: exoU and exoW probably encode glucosyltransferases.”  Becker A.et.al.   8118055
[4] “The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti.”  Finan T.M.et.al.   11481431

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTPTVNAKTV TRNVGWSVLS KTGTFGLKFV TVPILARILS PEEFGAVAVA LTVVQFLAMI 
61:	GGAGLTSALV IQQHEEMETV HSVFWANLAI ALMMALGLFV FAEPLATLLG APEAAYLLRI 
121:	MSLLIPLQLG GDVAYSLLVR RMNFRKDAVW SMISESLGAV IAVLLALLGF GIWSLLAQLF 
181:	VSALVRLSGL YAVSRYAPRF VFSLQRVLAL SRFSFGMMGS EIANFITFQS PMVVISRYLG 
241:	LSDAGAYSAA NRFASIPNQV VLSAVMGVLF PTFGQMMHDR ERRSQALMLS TQVTTVLLAP 
301:	MMFGLWALAE PAMLVLFGSQ WAYAWPVLGL LALSKGILTP CSTFIPYLKG VGQGAVLFWW 
361:	ALIRAVATTG AVAYGAIDGS LVEAMIWLCI VNAVTLVGYS WVVFRADSTP FLKGLFISSR 
421:	PMIAALLMAL VVRFLLEHFG AHVPNAVLQL IAGTAIGSVI YTVLILLTER SLLRRLLDMA 
481:	RARKPRAAPA GAAE