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2.A.67.2.1
'Yellow Stripe1' (YS1) Fe3+-phyto siderophore:H+ symporter. It takes up various metal cations (Fe3+, Zn2+, Cu2+, Ni2+, Mn2+ and Cd2+ when complexed with phytosiderophores, and Ni2+, Fe2+ and Fe3+ when complexed with nicotinamine) (Curie et al., 2001; Schaaf et al., 2004)

Accession Number:Q9AY27
Protein Name:YS1
Length:682
Molecular Weight:74418.00
Species:Zea mays (Maize) [4577]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Fe3+-phytosiderophore, Zn2+-phytosiderophore, Cu2+-phytosiderophore, Ni2+-phytosiderophore, Mn2+-phytosiderophore, Cd2+-phytosiderophore, Ni2+-nicotinamide, Fe2+-nicotinamide, Fe3+-nicotinamide, H+

Cross database links:

RefSeq: NP_001104952.1   
Entrez Gene ID: 541800   
Pfam: PF03169   
BioCyc: MetaCyc:MONOMER-14020   
KEGG: zma:541800   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0006826 P:iron ion transport
GO:0055085 P:transmembrane transport

References (3)

[1] “Maize yellow stripe1 encodes a membrane protein directly involved in Fe(III) uptake.”  Curie C.et.al.   11201743
[2] “ZmYS1 functions as a proton-coupled symporter for phytosiderophore- and nicotianamine-chelated metals.”  Schaaf G.et.al.   14699112
[3] “Yellow stripe1. Expanded roles for the maize iron-phytosiderophore transporter.”  Roberts L.A.et.al.   15107503

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDLARRGGAA GADDEGEIER HEPAPEDMES DPAAAREKEL ELERVQSWRE QVTLRGVVAA 
61:	LLIGFMYSVI VMKIALTTGL VPTLNVSAAL MAFLALRGWT RVLERLGVAH RPFTRQENCV 
121:	IETCAVACYT IAFGGGFGST LLGLDKKTYE LAGASPANVP GSYKDPGFGW MAGFVAAISF 
181:	AGLLSLIPLR KVLVIDYKLT YPSGTATAVL INGFHTKQGD KNARMQVRGF LKYFGLSFVW 
241:	SFFQWFYTGG EVCGFVQFPT FGLKAWKQTF FFDFSLTYVG AGMICSHLVN ISTLLGAILS 
301:	WGILWPLISK QKGEWYPANI PESSMKSLYG YKAFLCIALI MGDGTYHFFK VFGVTVKSLH 
361:	QRLSRKRATN RVANGGDEMA ALDDLQRDEI FSDGSFPAWA AYAGYAALTV VSAVIIPHMF 
421:	RQVKWYYVIV AYVLAPLLGF ANSYGTGLTD INMAYNYGKI ALFIFAAWAG RDNGVIAGLA 
481:	GGTLVKQLVM ASADLMHDFK TGHLTMTSPR SLLVAQFIGT AMGCVVAPLT FLLFYNAFDI 
541:	GNPTGYWKAP YGLIYRNMAI LGVEGFSVLP RHCLALSAGF FAFAFVFSVA RDVLPRKYAR 
601:	FVPLPMAMAV PFLVGGSFAI DMCVGSLAVF VWEKVNRKEA VFMVPAVASG LICGDGIWTF 
661:	PSSILALAKI KPPICMKFTP GS