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2.A.67.2.3
The metal (iron and copper)-nicotinamide transporter, YSL2 (mediates lateral movement of metals in the vasculature; DiDonato et al., 2004) (62% identity with YS1).

Accession Number:Q6R3K9
Protein Name:YSL2
Length:664
Molecular Weight:72983.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:15
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Fe2+-nicotinamide, Cu2+-nicotinamide

Cross database links:

Genevestigator: Q6R3K9
eggNOG: euNOG04038
HEGENOM: HBG606963
RefSeq: NP_197826.2   
Entrez Gene ID: 832509   
Pfam: PF03169   
KEGG: ath:AT5G24380   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006826 P:iron ion transport
GO:0010039 P:response to iron ion
GO:0010043 P:response to zinc ion
GO:0055085 P:transmembrane transport

References (4)

[1] “A putative function for the arabidopsis Fe-Phytosiderophore transporter homolog AtYSL2 in Fe and Zn homeostasis.”  Schaaf G.et.al.   15753101
[2] “Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence features of the regions of 1,081,958 bp covered by seventeen physically assigned P1 and TAC clones.”  Asamizu E.et.al.   10048488
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Arabidopsis Yellow Stripe-Like2 (YSL2): a metal-regulated gene encoding a plasma membrane transporter of nicotianamine-metal complexes.”  DiDonato R.J. Jr.et.al.   15255869

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MENERVEREQ SQFQEDEFID SRKPPPWRKQ ITVRAIVASL LIGIVYSVIC LKLNLTTGLV 
61:	PNLNISSALL AFVFLKSWTK VLQKAGIATT PFTRQENTIA QTCAVACYSI SLAGGFASYL 
121:	LGLNRRTYEE TGVNTEGNNP RGIKEPGVGW MTSFLFVTSF IGLVVLVPLR KVMIIDYKLT 
181:	YPSGTATAVL INGFHTSKGD KTAKKQIRGF IKSFGLSFFW AFFGWFYSGG EKCGFSQFPT 
241:	FGLQALDKTF YFDFSMTYVG AGMICSHLVN LSLLFGAILS WGIMWPLIAR LKGEWFPATL 
301:	KDNSMQGLNG YKVFICIALI LGDGLYNFVK ILFFTGRSFH SRLSKTNSIS TLVEVPEDST 
361:	KESDNLKREN EVFVRESIPL WMACVGYLFF SLVSIIAIPL MFPQLKWYFV LVAYLLAPSL 
421:	SFCNAYGAGL TDMNMAYNYG KAALFVMAAL AGKNDGVVAG MVACGLIKSI VSVSADLMHD 
481:	FKTGHLTQTS PRSMLVAQAI GTAIGCVVAP LTFFLFYKAF DVGNQNGEYK APYAMIYRNM 
541:	AIIGVQGPSA LPKHCLELCY GFFAFAVAAN LARDLLPDKP GKWIPLPMAM AVPFLVGGSF 
601:	AIDMCIGSLV VYVWKKVNRK KADVMVPAVA SGLICGDGLW ILPSSLLALA KVRPPICMNF 
661:	TAAH