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2.A.67.2.4
The probable metal (iron, copper, and zinc)-nicotinamide transporter, YSL3; functionally redundant with YSL1 (Waters et al., 2006).

Accession Number:Q2EF88
Protein Name:YSL3
Length:675
Molecular Weight:74149.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:16
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Fe2+-nicotinamide, Cu2+-nicotinamide, Zn2+-nicotinamide

Cross database links:

Genevestigator: Q2EF88
eggNOG: euNOG04038
HEGENOM: HBG606963
RefSeq: NP_200167.2   
Entrez Gene ID: 835437   
Pfam: PF03169   
KEGG: ath:AT5G53550   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0006826 P:iron ion transport
GO:0009624 P:response to nematode
GO:0055085 P:transmembrane transport

References (2)

[1] “Mutations in Arabidopsis yellow stripe-like1 and yellow stripe-like3 reveal their roles in metal ion homeostasis and loading of metal ions in seeds.”  Waters B.M.et.al.   16815956
[2] “Structural analysis of Arabidopsis thaliana chromosome 5. VII. Sequence features of the regions of 1,013,767 bp covered by sixteen physically assigned P1 and TAC clones.”  Nakamura Y.et.al.   9872454

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRSMMMEREG RNEIEREVID DLEETQNEGD DFKSIPPWKE QITFRGIVAS LIIGIIYSVI 
61:	VMKLNLTTGL VPNLNVSAAL LAFVFLRSWT KLLTKAGIVT KPFTKQENTV VQTCAVACYS 
121:	IAVGGGFGSY LLGLNRITYE QSGGTHTDGN YPEGTKEPGI GWMTAFLFFT CFVGLLALVP 
181:	LRKIMIIDYK LTYPSGTATA VLINGFHTPK GNKMAKKQVF GFVKYFSFSF IWAFFQWFFS 
241:	GGTECGFIQF PTFGLEALKN TFYFDFSMTY VGAGMICPHI VNISLLFGAV LSWGIMWPLI 
301:	KGLKGDWFPS TLPENSMKSL NGYKVFISIS LILGDGLYQF IKILFKTGIN MYVKLNNRNS 
361:	GKSNSEKDKQ SIADLKRDEI FVRDSIPLWV AAVGYAAFSV VSIIAIPIMF PELKWYFIVV 
421:	AYMLAPSLGF SNAYGAGLTD MNMAYNYGKV ALFILAAMAG KQNGVVAGLV GCGLIKSIVS 
481:	ISSDLMHDFK TGHLTLTSPR SMLVSQAIGT AIGCVVAPLT FFLFYKAFDV GNQEGEYKAP 
541:	YALVYRNMAI LGVEGFSALP QHCLQLCYGF FAFAVAANLV RDRLPDKIGN WVPLPMAMAV 
601:	PFLVGGYFAI DMCVGSLIVF AWNMRDRVKA GLMVPAVASG LICGDGLWIL PSSVLALAGV 
661:	RPPICMGFMP SKYSS