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2.A.69.1.2
Auxin transporter, ethylene-insensitive root 1 (EIR1) auxin:H+ symporter

Accession Number:Q9LU77
Protein Name:Auxin efflux carrier component 2
Length:647
Molecular Weight:69331.00
Species: [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Auxin

Cross database links:

Genevestigator: Q9LU77
HEGENOM: HBG319549
RefSeq: NP_568848.1   
Entrez Gene ID: 835813   
Pfam: PF03547   
KEGG: ath:AT5G57090   

Gene Ontology

GO:0009925 C:basal plasma membrane
GO:0016021 C:integral to membrane
GO:0000323 C:lytic vacuole
GO:0010329 F:auxin efflux transmembrane transporter acti...
GO:0009734 P:auxin mediated signaling pathway
GO:0009926 P:auxin polar transport
GO:0009958 P:positive gravitropism
GO:0009723 P:response to ethylene stimulus
GO:0009749 P:response to glucose stimulus
GO:0055085 P:transmembrane transport

References (6)

[1] “EIR1, a root-specific protein involved in auxin transport, is required for gravitropism in Arabidopsis thaliana.”  Luschnig C.et.al.   9679062
[2] “The Arabidopsis thaliana AGRAVITROPIC 1 gene encodes a component of the polar-auxin-transport efflux carrier.”  Chen R.et.al.   9844024
[3] “Agr, an Agravitropic locus of Arabidopsis thaliana, encodes a novel membrane-protein family member.”  Utsuno K.et.al.   9871369
[4] “AtPIN2 defines a locus of Arabidopsis for root gravitropism control.”  Mueller A.et.al.   9843496
[5] “Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones.”  Sato S.et.al.   10718197
[6] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MITGKDMYDV LAAMVPLYVA MILAYGSVRW WGIFTPDQCS GINRFVAVFA VPLLSFHFIS 
61:	SNDPYAMNYH FLAADSLQKV VILAALFLWQ AFSRRGSLEW MITLFSLSTL PNTLVMGIPL 
121:	LRAMYGDFSG NLMVQIVVLQ SIIWYTLMLF LFEFRGAKLL ISEQFPETAG SITSFRVDSD 
181:	VISLNGREPL QTDAEIGDDG KLHVVVRRSS AASSMISSFN KSHGGGLNSS MITPRASNLT 
241:	GVEIYSVQSS REPTPRASSF NQTDFYAMFN ASKAPSPRHG YTNSYGGAGA GPGGDVYSLQ 
301:	SSKGVTPRTS NFDEEVMKTA KKAGRGGRSM SGELYNNNSV PSYPPPNPMF TGSTSGASGV 
361:	KKKESGGGGS GGGVGVGGQN KEMNMFVWSS SASPVSEANA KNAMTRGSST DVSTDPKVSI 
421:	PPHDNLATKA MQNLIENMSP GRKGHVEMDQ DGNNGGKSPY MGKKGSDVED GGPGPRKQQM 
481:	PPASVMTRLI LIMVWRKLIR NPNTYSSLFG LAWSLVSFKW NIKMPTIMSG SISILSDAGL 
541:	GMAMFSLGLF MALQPKIIAC GKSVAGFAMA VRFLTGPAVI AATSIAIGIR GDLLHIAIVQ 
601:	AALPQGIVPF VFAKEYNVHP DILSTAVIFG MLVALPVTVL YYVLLGL