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2.A.69.1.3
Auxin efflux carrier, PIN7 (promotes embryonic axis formation) (Friml et al., 2003)

Accession Number:Q940Y5
Protein Name:PIN7
Length:619
Molecular Weight:67588.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Auxin

Cross database links:

Genevestigator: Q940Y5
HEGENOM: HBG319549
RefSeq: NP_564189.1    NP_849700.1   
Entrez Gene ID: 838916   
Pfam: PF03547   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0010329 F:auxin efflux transmembrane transporter acti...
GO:0009734 P:auxin mediated signaling pathway
GO:0009926 P:auxin polar transport
GO:0009942 P:longitudinal axis specification
GO:0048364 P:root development
GO:0055085 P:transmembrane transport

References (4)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “Efflux-dependent auxin gradients establish the apical-basal axis of Arabidopsis.”  Friml J.et.al.   14614497
[4] “Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.”  Reiland S.et.al.   19376835

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MITWHDLYTV LTAVIPLYVA MILAYGSVRW WKIFSPDQCS GINRFVAIFA VPLLSFHFIS 
61:	SNNPYAMNLR FIAADTLQKL IMLTLLIIWA NFTRSGSLEW SITIFSLSTL PNTLVMGIPL 
121:	LIAMYGEYSG SLMVQIVVLQ CIIWYTLLLF LFEYRGAKIL IMEQFPETGA SIVSFKVESD 
181:	VVSLDGHDFL ETDAQIGDDG KLHVTVRKSN ASRRSFYGGG GTNMTPRPSN LTGAEIYSLN 
241:	TTPRGSNFNH SDFYSMMGFP GGRLSNFGPA DMYSVQSSRG PTPRPSNFEE SCAMASSPRF 
301:	GYYPGGAPGS YPAPNPEFST GNKTGSKAPK ENHHHVGKSN SNDAKELHMF VWGSNGSPVS 
361:	DRAGLQVDNG ANEQVGKSDQ GGAKEIRMLI SDHTQNGENK AGPMNGDYGG EEESERVKEV 
421:	PNGLHKLRCN STAELNPKEA IETGETVPVK HMPPASVMTR LILIMVWRKL IRNPNTYSSL 
481:	IGLIWALVAF RWDVAMPKII QQSISILSDA GLGMAMFSLG LFMALQPKLI ACGNSTATFA 
541:	MAVRFFTGPA VMAVAAMAIG LRGDLLRVAI VQAALPQGIV PFVFAKEYNV HPAILSTGVI 
601:	FGMLIALPIT LVYYILLGL