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2.A.69.4.5
Malate permease, MleP (Labarre et al. 1996). Activated a few minutes after rehydration (Costantini et al. 2011).

Accession Number:Q48797
Protein Name:MleP
Length:314
Molecular Weight:34199.00
Species:Oenococcus oeni (Leuconostoc oenos) [1247]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate malate

Cross database links:

Pfam: PF03547   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0055085 P:transmembrane transport

References (2)

[1] “Cloning and characterization of the genes encoding the malolactic enzyme and the malate permease of Leuconostoc oenos.”  Labarre C.et.al.   8919788
[2] “Genetic organization of the mle locus and identification of a mleR-like gene from Leuconostoc oenos.”  Labarre C.et.al.   8953720

External Searches:

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  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNAFITSVES VVEIVLVIAL GYVLRRSGKL ADSFKGNISY LIMNIALPLS IFVSVLTYLT 
61:	RDKLVSLSGG LVFAAASFAV SYVLAYLITK IFKIRVGRRG TFINMFVNAN TIFIGLPLNS 
121:	ALFGTKSMPY FLIYYVMNTI STWAIGIFFI SSDDPTRDKT EKQSFNWKKL LPMPLVGFLI 
181:	SIVVLLLAIP IPGWVSTTFS MVGGIVTPMS LIYIGIILAD AGLKSIHFDR DSILALIGRF 
241:	IIVPAVMIII LKLFGGSMPK LESSTLIIQA AAPGLAVLPI LVGQNHGDVE YATNVVTTST 
301:	VLFVIVVPIL MQFV