TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.7.10.1
UDP-N-acetylglucosamine:UMP antiporter

Accession Number:Q00974
Protein Name:MNN2 aka Mnn2-2
Length:328
Molecular Weight:36667.00
Species:Kluyveromyces lactis (Yeast) [28985]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate UDP-N-acetylglucosamine, UMP

Cross database links:

eggNOG: fuNOG09381
HEGENOM: HBG737529
RefSeq: XP_451673.1   
Entrez Gene ID: 2897052   
Pfam: PF08449   
KEGG: kla:KLLA0B03157   

Gene Ontology

GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0005338 F:nucleotide-sugar transmembrane transporter ...
GO:0015780 P:nucleotide-sugar transport
GO:0055085 P:transmembrane transport

References (2)

[1] “Molecular cloning of the Golgi apparatus uridine diphosphate-N-acetylglucosamine transporter from Kluyveromyces lactis.”  Abeijon C.et.al.   8650202
[2] “Genome evolution in yeasts.”  Dujon B.et.al.   15229592

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSFVLILSLV FGGCCSNVIS FEHMVQGSNI NLGNIVTFTQ FVSVTLIQLP NALDFSHFPF 
61:	RLRPRHIPLK IHMLAVFLFF TSSVANNSVF KFDISVPIHI IIRCSGTTLT MIIGWAVCNK 
121:	RYSKLQVQSA IIMTLGAIVA SLYRDKEFSM DSLKLNTDSV GMTQKSMFGI FVVLVATALM 
181:	SLLSLLNEWT YNKCGKHWKE TLFYSHFLAL PLFMLGYTRL RDEFRDLLIS SDSMDIPIVK 
241:	LPIATKLFML IANNVTQFIC IKGVNMLASN TDALTLSVVL LVRKFVSLLL SVYIYKNVLS 
301:	VTAYLGTITV FLGAGLYSYG SVKTALPR