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2.A.7.10.5
ER/Golgi UDP-N-acetylglucosamine transporter, Yea4 of 342 aas.  Required for chitin biosynthesis (Roy et al. 2000).  Extracellular UDP-sugars promote cellular responses by interacting with widely distributed P2Y(14) receptors, and the ER/Golgi lumen constitutes a source of extracellular UDP-sugars (Sesma et al. 2009).  Yea4 therefore plays a critical role in nucleotide sugar-promoted cell signaling.

Accession Number:P40004
Protein Name:UDP-N-acetylglucosamine transporter YEA4
Length:342
Molecular Weight:39266.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Endoplasmic reticulum1
Substrate UDP-N-acetylglucosamine

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MWNSLKAFAL VFGGCCSNVI TFETLMSNET GSINNLITFC QFLFVTCQGL PEFLDVHQPF 
61:	PYFKPLKTPL HVYVITVVLF YISSTTNNNV FKYNISIPIH IVFRCFGTVI TMFTCWLLNG 
121:	RKYTKIQILS TLFLTIGAII ASLFKDADFR YQDLKLQAWK IGSDQSVDLT FIFGICILVL 
181:	SSFTSSLLSA YNERTYQKYG KHWKENIFYS HFLSLPLFLF SRKQLIHEYR VMRKSERILC 
241:	SNFGGKILVP REETLLLFNV LTQYFCVKGV NILASKTNAL TLSITLLVRK FISLLLSVRL 
301:	FDNNLSYTGY IGVYLVFFGA FIYSLGSIHP RQNDKGAIKK SK