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2.A.7.11.2
Golgi adenosine 3'-phosphate 5'-phosphosulfate transporter, slalom (functions by an exchange mechanism, essential for viability (Kamiyama et al., 2003)).

Accession Number:Q9VEI3
Protein Name:Adenosine 3'-phospho 5'-phosphosulfate transporter 1 aka PAPS transporter 1 aka Protein slalom
Length:465
Molecular Weight:52282.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate Adenosine 3'-phosphate 5'-phosphosulfate

Cross database links:

eggNOG: inNOG05566
RefSeq: NP_524389.1   
Entrez Gene ID: 42115   
Pfam: PF08449   
KEGG: dme:Dmel_CG7623   

Gene Ontology

GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0046964 F:3'-phosphoadenosine 5'-phosphosulfate trans...
GO:0046963 P:3'-phosphoadenosine 5'-phosphosulfate trans...
GO:0007310 P:oocyte dorsal/ventral axis specification
GO:0055085 P:transmembrane transport

References (5)

[1] “Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporter.”  Kamiyama S.et.al.   12716889
[2] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132
[3] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572
[4] “A Drosophila full-length cDNA resource.”  Stapleton M.et.al.   12537569
[5] “Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila.”  Lueders F.et.al.   12853478

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MYAYNKMGRV PELVICSFIV VTLLVIHFFS DLLRASLGGY YNQDVTLSQL VESQNSDYAW 
61:	FLKLLVNCFG YSCVFVPGFL IYKYVGRINY LERGNKTFLH KAINMCITGN SGYDQLDAGT 
121:	STADKDRPAA STAPKRTSSQ EAVQLLWCFG GLMISYLTWG VLQEKIMTQN YLNFTGESAK 
181:	FKDSQFLVFS NRLLAFLVAL AYLQWQPSPV RHRAPLYKYS YASFSNIMSA WFQYEALKFV 
241:	NFPTQVLAKS CKIIPVMLMG KIMSKAKYES YEYVTALLIS LGMIFFMSGS SDSSKASGVT 
301:	TLTGIFLLSM YMVFDSFTAN WQGSLFKSYG MTPLQMMCGV NLFSSIFTGA SLSMQGGFMD 
361:	SLAFATEHPK FVFDMVVLSV CSAVGQLFIY HTIDVFGPVV FTIIMTLRQA VAIMLSCFIY 
421:	QHSISLLGIF GVLIVFVAIF LRVYCTQRLR AIRKRAEANK PKMAV