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2.A.7.12.10
The ZK896.9 Golgi apparatus nucleotide-sugar transporter (transports UDP-glucose, UDP-galactose, UDP-N-acetylglucosamine, and UDP-N-acetylgalactosamine) (Caffaro et al., 2008)

Accession Number:O02345
Protein Name:ZK896.9
Length:390
Molecular Weight:42981.00
Species:Caenorhabditis elegans GN=ZK896.9 PE=2 SV=1 [6239]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate UDP-glucose, UDP-galactose, UDP-N-acetylglucosamine, UDP-N-acetylgalactosamine

Cross database links:

eggNOG: meNOG04090
HEGENOM: HBG608296
RefSeq: NP_502448.1   
Entrez Gene ID: 191452   
Pfam: PF04142   
KEGG: cel:ZK896.9   

Gene Ontology

GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0005338 F:nucleotide-sugar transmembrane transporter ...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009792 P:embryonic development ending in birth or eg...
GO:0007052 P:mitotic spindle organization
GO:0015780 P:nucleotide-sugar transport

References (1)

[1] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGLTKAETIK YSSLVVLVVQ NCSLVLFMRY AMTKDRPKFL KTITVLFGEI FKCTVSLLLA 
61:	CIEEKSIAKG LRKIHHEFFV NWRDTLKVLV PSAIYTVQNF LLYVAVDNLP AATYMVTYQL 
121:	KILTTAAFTV LVLHRRLTIQ QWISLFVLFA GVVVVQYDQK MSNEREKAAA AAVLSSTLAP 
181:	TTTVSPFSNL TTTLTTVVTT ASLASSKTEN SVLGFIAVLI ACVLSGFAGI YFEKILKGSN 
241:	VSIWIRNIQL AFPSIFFAFL FASVKDNSSL YQDGPNPIEI WNNMLQGFDW AVWVTVAINA 
301:	FGGLVVAVVI KYADNILKAF ATSLAIVLNC IAAYFLFNFR PSILFLVGAS GVIAAVFAYS 
361:	MYPYKASHQA LPTDAPKEVE LQPVVESSKS